Genetics: From Genes to Genomes - Brossura

Hartwell, Leland

Brossura

ISBN 10: 0071221921 ISBN 13: 9780071221924

Casa editrice: McGraw-Hill Education, 2010

Riassunto

Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The Third Edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the new molecular discoveries that have changed the way the field of genetics is viewed.

Su questo libro

L'autore:

Dr. Leland Hartwell is President and Director of Seattles Fred Hutchinson CancerResearch Center and Professor of Genome Sciences at the University of Washington.Dr. Hartwells primary research contributions were in identifying genes that controlcell division in yeast, including those necessary for the division process as well asthose necessary for the fi delity of genome reproduction. Subsequently, many of thesesame genes have been found to control cell division in humans and oft en to be thesite of alteration in cancer cells.Dr. Hartwell is a member of the National Academy of Sciences and has receivedthe Albert Lasker Basic Medical Research Award, the Gairdner FoundationInternational Award, the Genetics Society Medal, and the 2001 Nobel Prize inPhysiology or Medicine.

Contenuti:

Genetics: The Study of Biological Information

PART I Basic Principles: How Traits Are Transmitted
2 Mendel’s Breakthrough: Patterns, Particles, and Principles of Heredity
3 Extensions to Mendel: Complexities in Relating Genotype to Phenotype
4 The Chromosome Theory of Inheritance
5 Linkage, Recombination, and the Mapping of Genes on Chromosomes
PART II What Genes Are and What They Do
6 DNA: Structure, Replication, and Recombination
7 Anatomy and Function of a Gene: Dissection Through Mutation
8 Gene Expression: The Flow of Information from DNA to RNA to Proteinv
PART III Analysis of Genetic Information
9 Digital Analysis of DNA
10 Genomes and Proteomes
11 Genome-Wide Variation and Trait Analysis
PART IV How Genes Travel on Chromosomes
12 The Eukaryotic Chromosome
13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes
14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria
PART V How Genes Are Regulated
15 Gene Regulation in Prokaryotes
16 Gene Regulation in Eukaryotes
17 Somatic Mutation and the Genetics of Cancer
18 Using Genetics to Study Development
PART VI Genetics Beyond the Individual
19 Variation and Selection in Populations
20 Evolution at the Molecular Level
PART VIII Systems Biology
21 Systems Biology and the Future of Medicine

Su questa edizione

• Editore: McGraw-Hill Education
• Data di pubblicazione: 2010
• ISBN 10: 0071221921
• ISBN 13: 9780071221924
• Rilegatura: Copertina flessibile
• Numero edizione: 4
• Numero di pagine: 960