Genetics: From Genes to Genomes - Rilegato

Hartwell, Leland; Hood, Leroy; Goldberg, Michael; Reynolds, Ann E.; Silver, Lee

Rilegato

ISBN 10: 007352526X ISBN 13: 9780073525266

Casa editrice: McGraw-Hill Education, 2010

Riassunto

Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The 4th edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed.

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Su questo libro

L'autore:

Dr. Leland Hartwell is President and Director of Seattles Fred Hutchinson CancerResearch Center and Professor of Genome Sciences at the University of Washington.Dr. Hartwells primary research contributions were in identifying genes that controlcell division in yeast, including those necessary for the division process as well asthose necessary for the fi delity of genome reproduction. Subsequently, many of thesesame genes have been found to control cell division in humans and oft en to be thesite of alteration in cancer cells.Dr. Hartwell is a member of the National Academy of Sciences and has receivedthe Albert Lasker Basic Medical Research Award, the Gairdner FoundationInternational Award, the Genetics Society Medal, and the 2001 Nobel Prize inPhysiology or Medicine.

Contenuti:

Chapter: 1 Genetics: The Study of Biological Information

PART I Basic Principles: How Traits Are Transmitted

Chapter: 2 Mendel's Breakthrough: Patterns, Particles, and Principles of Heredity

Chapter: 3 Extensions to Mendel: Complexities in Relating Genotype to Phenotype

Chapter: 4 The Chromosome Theory of Inheritance

Chapter: 5 Linkage, Recombination, and the Mapping of Genes on Chromosomes

PART II What Genes Are and What They Do

Chapter: 6 DNA: Structure, Replication, and Recombination

Chapter: 7 Anatomy and Function of a Gene: Dissection Through Mutation

Chapter: 8 Gene Expression: The Flow of Information from DNA to RNA to Proteinv

PART III Analysis of Genetic Information

Chapter: 9 Digital Analysis of DNA

Chapter: 10 Genomes and Proteomes

Chapter: 11 Genome-Wide Variation and Trait Analysis

PART IV How Genes Travel on Chromosomes

Chapter: 12 The Eukaryotic Chromosome

Chapter: 13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes

Chapter: 14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria

PART V How Genes Are Regulated

Chapter: 15 Gene Regulation in Prokaryotes

Chapter: 16 Gene Regulation in Eukaryotes

Chapter: 17 Somatic Mutation and the Genetics of Cancer

Chapter: 18 Using Genetics to Study Development

PART VI Genetics Beyond the Individual

Chapter: 19 Variation and Selection in Populations

Chapter: 20 Evolution at the Molecular Level

PART VIII Systems Biology

Chapter: 21 Systems Biology and the Future of Medicine

Su questa edizione

• Editore: McGraw-Hill Education
• Data di pubblicazione: 2010
• ISBN 10: 007352526X
• ISBN 13: 9780073525266
• Rilegatura: Copertina rigida
• Numero edizione: 4
• Numero di pagine: 730