Genetics: From Genes to Genomes - Brossura

Hartwell Dr., Leland; Goldberg MD, Michael L.; Fischer Author, Janice; Hood Dr., Leroy; Aquadro, Charles (Chip)

Brossura

ISBN 10: 0073525316 ISBN 13: 9780073525310

Casa editrice: McGraw-Hill Education, 2014

Riassunto

Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The 5th edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed.
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Su questo libro

L'autore:

Dr. Leland Hartwell is President and Director of Seattles Fred Hutchinson CancerResearch Center and Professor of Genome Sciences at the University of Washington.Dr. Hartwells primary research contributions were in identifying genes that controlcell division in yeast, including those necessary for the division process as well asthose necessary for the fi delity of genome reproduction. Subsequently, many of thesesame genes have been found to control cell division in humans and oft en to be thesite of alteration in cancer cells.Dr. Hartwell is a member of the National Academy of Sciences and has receivedthe Albert Lasker Basic Medical Research Award, the Gairdner FoundationInternational Award, the Genetics Society Medal, and the 2001 Nobel Prize inPhysiology or Medicine.

Dr. Michael Goldberg is a professor at Cornell University, where he teaches introductorygenetics and human genetics. He was an undergraduate at Yale Universityand received his Ph.D. in biochemistry from Stanford University. Dr. Goldberg performedpostdoctoral research at the Biozentrum of the University of Basel (Switzerland)and at Harvard University, and he received an NIH Fogarty Senior InternationalFellowship for study at Imperial College (England) and fellowships from theFondazione Cenci Bolognetti for sabbatical work at the University of Rome (Italy).His current research uses the tools of Drosophila genetics and the biochemical analysisof frog egg cell extracts to investigate the mechanisms that ensure proper cellcycle progression and chromosome segregation during mitosis and meiosis.

Dr. Janice Fischer is a Professor at The University of Texas at Austin, where she is an award-winning teacher of genetics and Director of the Biology Instructional Office. She received her Ph.D. in biochemistry and molecular biology from Harvard University, and did postdoctoral research at The University of California at Berkeley and The Whitehead Institute at MIT. In her current research, Dr. Fischer uses Drosophila to examine the roles of ubiquitin and endocytosis in cell signaling during development.

Dr. Hood received an MD from the Johns Hopkins Medical Schooland a PhD in Biochemistry from the California Institute of Technology. His research interests include immunology, development and the development of biological instrumentation (e.g. the protein sequenator and the automated fluorescent DNA sequencer). His research played a key role in unraveling the mysteries of anitbody diversity. Dr. Hood has taught molecular evolution, immunology, molecular biology and biochemistry. he is currently the Chairman (and founder) of the cross-disciplinary Department of Molecular Biotechnology at the University of Washington. Dr. Hood has received a variety of awards including the Albert Lasker Award for Medical Research (1987), Dickson Price (1987), Cefas Award for Biochemistry (1989), and the Distinguished Service Award from the national Association of Teachers (1998). He is deeply involved in K-12 science educatiohn. His hobbies include running, mountain climbing, and reading.

Dr. Charles Aquadro (Chip) is Professor of Population Genetics, the Charles A. Alexander Professor of Biological Sciences, and Director of the Center for Comparative and Population Genomics at Cornell University. He obtained his Ph.D. in genetics from the University of Georgia, was a postdoc at the National Institute for Environmental Health Sciences/NIH, and joined the faculty at Cornell University in 1985 where he is now a professor. He has served as President of the Society of Molecular Biology and Evolution, is an elected Fellow of the AAAS, is a member of the Scientific Advisory Board for National Geographic Societys Genographic Project, was a member of the Scientific Advisory Board for the WGBH/NOVA TV series Evolution, and has been a visiting scholar at Cambridge University (England, 1993) and Harvard University (2007). His research and teaching focuses on molecular population genetics, molecular evolution, and comparative genomics. While Drosophila is his primary research system, recent work has also involved yeast, humans, and plants. At Cornell, he teaches a university-wide course to nonmajors on personal genomics and medicine, and a majors course in population genetics.

Contenuti:

1.Genetics: The Study of Biological Information
2.Mendel’s Principles of Heredity
3.Extensions to Mendel’s Laws
4.The Chromosome Theory of Inheritance
5.Linkage, Recombination, and the Mapping of Genes on Chromosomes
6.DNA Structure, Replication, and Recombination
7.Anatomy and Function of a Gene: Dissection Through Mutation
8.Gene Expression: The Flow of Information from DNA to RNA to Protein
9. Digital Analysis of Genomes
10. Analyzing Genomic Variation
11.The Eukaryotic Chromosome
12.Chromosomal Rearrangements and Changes in Chromosome Number
13.Bacterial Genetics
14.Organellar Inheritance
15.Gene Regulation in Prokaryotes
16.Gene Regulation in Eukaryotes
17.Manipulating the Genomes of Eukaryotes
18.The Genetic Analysis of Development
19.The Genetics of Cancer
20.Variation and Selection in Populations
21.Genetics of Complex Traits

Su questa edizione

• Editore: McGraw-Hill Education
• Data di pubblicazione: 2014
• ISBN 10: 0073525316
• ISBN 13: 9780073525310
• Rilegatura: Copertina flessibile
• Numero edizione: 5
• Numero di pagine: 816