Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity: 47 - Rilegato

Rilegato

ISBN 10: 0121533476 ISBN 13: 9780121533472

Casa editrice: Academic Pr, 1999

Riassunto

Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via the ouabain-sensitive sodium/potassium ATPase. The sodium entry channels are the rate-limiting determinant for transport and are regulated by several different hormones. The sodium channels also play a significant role in a number of disease states, like hypertension, edema, drug-induced hyperkalemia, and cystic fibrosis. Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity provides the first in-depth exchange of ideas concerning these sodium channels, their regulation and involvement in normal and pathophysiological situations.

• Summarizes current state of amiloride-sensitive sodium channel field
• Analyzes structure-function of epithelial sodium channels
• Discusses immunolocalization of epithelial sodium channels
• Examines hormonal regulation of sodium channels
• Discusses sodium channels in lymphocytes, kidney, and lung
• Considers mechanosensitivity of sodium channels
• Provides ideas on sodium channels and disease

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Su questa edizione

• Editore: Academic Pr
• Data di pubblicazione: 1999
• ISBN 10: 0121533476
• ISBN 13: 9780121533472
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 384
• Redattore: Benos Dale J.