Osteoporosis - Rilegato

Rilegato

ISBN 10: 0124158536 ISBN 13: 9780124158535

Casa editrice: Academic Press, 2013

Riassunto

Now in its fourth edition, Osteoporosis is a classic reference on this disease, comprising a tremendous wealth of knowledge in a single source not found elsewhere. Written by renowned experts in the field, this two-volume work is a must-have for academic and medical libraries, physicians, researchers, and any company involved in osteoporosis research and development. This newest edition covers everything from basic anatomy and physiology to diagnosis, management and treatment in which direct care costs for osteoporotic fractures in the United States reach up to $18 billion each year. Worldwide, 200 million women ages 60 to 80 suffer from osteoporosis and have a lifetime risk of fracture between 30% and 40%, continuing to make osteoporosis a critical challenge in medicine.

• Recognizes the critical importance of the Wnt signaling pathway for bone health
• Incorporates new chapters on osteocytes, phosphatonins, mouse genetics, and CNS and bone
• Examines essential updates on estrogen prevention and treatment and the recent results from the WHO
• Discusses the controversial topics of screening and clinical trial design for drug registration
• Includes essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, and parathyroid hormone
• Offers critical reviews of reproductive and hormonal risk factors, ethnicity, nutrition, therapeutics, management, and economics

Su questo libro

Recensione:

Praise for Previous Edition:
"...Osteoporosis is quite comprehensive; indeed, topics that typically receive brief treatment elsewhere (osteoporosis in minority groups and in men) receive entire chapters here..."--THE NEW ENGLAND JOURNAL OF MEDICINE

L'autore:

Dr. Marcus is Professor-Emeritus, Stanford University, where he served on the full-time medical faculty for almost 25 years, before joining the Emeritus faculty in 2001. At Stanford, he was located at the Veterans Affairs Medical Center, Palo Alto California, where he served as Director of the Aging Study Unit of the Geriatrics Research, Education, & Clinical Center from 1982-2001. Dr. Marcus enjoyed a long career as a clinical investigator in the fields of bone and mineral metabolism and osteoporosis medicine. His own research interests included diagnosis and therapy of primary hyperpara-thyroidism, interactions of the parathyroid-vitamin D axis with estrogen, age-related changes in the growth hormone-IGF axis, effects of growth hormone replacement for older men and women, metabolic and musculoskeletal effects of resistance exercise in older men and women, adolescent bone acquisition, and osteoporosis therapeutics. Dr. Marcus’ laboratory was a study site for many of the pivotal clinical trials in the osteoporosis field. These include the NIH Post-menopausal Estrogen/Progestin Interventions Trial (PEPI), Merck’s Fracture Intervention Trial (FIT), Lilly’s Multiple Outcomes of Raloxifene Intervention (MORE), and Lilly’s registration trial of recombinant PTH(1-34) in the treatment of postmenopausal women with osteoporosis. In 2001. Dr. Marcus joined the US Affiliate of Eli Lilly & Company to support Lilly’s program in Osteoporosis and Skeletal Medicine. From 2003 until his retirement from Lilly in 2008, Dr. Marcus was the lead physician for the Forteo team at Lilly. He has published more than 150 research papers, editorials, and reviews. Dr. Marcus served as President of the American Society for Bone & Mineral Research in 2000-2001.

Su questa edizione

• Editore: Academic Press
• Data di pubblicazione: 2013
• ISBN 10: 0124158536
• ISBN 13: 9780124158535
• Rilegatura: Copertina rigida
• Numero edizione: 4
• Numero di pagine: 2116
• Redattore: Marcus MD Robert, Dempster Dr. David W., Cauley Jane A., Feldman David