Chromatin Signaling and Neurological Disorders: Volume 12 - Rilegato

Rilegato

ISBN 10: 0128137967 ISBN 13: 9780128137963

Casa editrice: Academic Pr, 2019

Riassunto

Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin and epigenetic signaling pathways and specific chromatin signaling factors that regulate a range of diseases.

In addition to the basic science of chromatin signaling factors, each disease-specific chapter speaks to the translational or clinical significance of recent findings, along with important implications for the development of epigenetics-based therapeutics. Common themes of translational significance are also identified across disease types, as well as the future potential of chromatin signaling research.

• Examines specific chromatin signaling factors that regulate spinal muscular atrophy, ulbospinal muscular atrophy, amyotrophic lateral sclerosis, Parkinson's disease, Huntington's disease, multiple sclerosis, Angelman syndrome, Rader-Willi syndrome, and more
• Contains chapter contributions from international experts who speak to the clinical significance of recent findings and the implications for the development of epigenetics-based therapeutics
• Provides researchers, students and clinicians with approaches to better interpret and employ new diagnostic studies for treating neurological disorders

Su questo libro

Informazioni sull?autore

Dr. Olivier Binda is a Researcher at the University of Ottawa, specializing in epigenetics and gene expression as it relates to human diseases. Dr. Binda co-edited Chromatin Signaling and Diseases (Elsevier 2016), a volume in Elsevier’s Translational Epigenetics series, and has published 20 scientific papers in such peer reviewed journals as the Molecular Cell, Journal of Biological Chemistry, Biochemistry, Epigenetics, Oncogene, Scientific Reports, and Stem Cell Research. In past positions he has served as a postdoctoral fellow at McGill University and Stanford University, and he completed his PhD in Biochemistry at McGill University in 2007.

Affiliations and expertise

University of Ottawa, Department of Cellular and Molecular Medicine, Ottawa, CANADA.

Dettagli dell?edizione

• Editore: Academic Pr
• Data di pubblicazione: 2019
• Lingua: Inglese
• ISBN 10: 0128137967
• ISBN 13: 9780128137963
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 544
• Redattore: Binda Olivier
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile