Oxygen radicals are highly reactive forms of oxygen that upset the body's normal chemistry. They are created by the reaction of oxygen with radiation, air pollution, and other environmental agents, or generated in metabolism by one-electron transfers to an unstable oxygen molecule. Reactive species of oxygen and the damage they cause have been implicated in a variety of diseases. This volume focuses on their possible role in cardiovascular disease and cancer. It examines the molecular mechanisms by which oxidative damage occurs, the consequences of that damage, and some of the ways in which the damage might be mitigated. The book is based on a study group sponsored by the Conte Institute for Environmental Health, Pittsfield, Massachusetts.
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Arthur D. Bloom, President, The Conte Institute for Environmental Health.Review:
"The literature quoted in each chapter is carefully selected . . . . Most of the chapters are easy to read, even without special knowledge in free radical chemistry and methodology. I enjoyed reading this excellent book and I recommend it highly, particularly to all those interested in
implications of free radicals in cardiovascular disease and cancer." --H. Esterbauer, Free Radical Research Communications
"This Monograph was produced by a group of Fellows of the Silvio O. Conte Institute for Environment Health with the purpose to evaluate the ways in which environment agents modulate oxidative damage in the pathogenesis of cancer and cardiovascular disease. This is a quite timely task. . .
These authors, most of them already known in the field, have provided competent brief overviews on the topics addressed. . . the range covered is quite large, and the booklet may serve well in generating further interest."-- Helmut Sies, Ph.D., Inst. Physiologische Chemie I interest.
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Descrizione libro Oxford University Press, USA, 1992. Hardcover. Condizione libro: New. 1. Codice libro della libreria DADAX0195072960