Antisense Technology in the Central Nervous System - Rilegato

Rilegato

ISBN 10: 0198503164 ISBN 13: 9780198503163

Casa editrice: OUP Oxford, 1999

Riassunto

Antisense technology has been used for several years to "knock down" the expression of specific genes in living tissues to study the functions of their protein products. Specifically designed antisense oligonucleotides (ODNs) are short lengths of man-made genetic material designed to interfere with the production of the protein encoded by the gene. This can shed light on the function of the protein; alternatively, if a disease process results from an excess of a certain protein, the method can in theory correct the problem. Faster than transgenic techniques, but more similarly problematic in practice, antisense has been seen as something of a "black art". There are many technical problems to understand and overcome. This is the first book to provide a critical review of the uses of this technology in the central nervous system. Antisense Technology in the Central Nervous System describes the promises and the pitfalls of this approach, and compares it to other approaches. The practical experience of leading researchers is combined with a thorough description of the theoretical foundation of the technique, making the book ideal for researchers and clinicians alike.

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Dettagli dell'edizione

• Editore: OUP Oxford
• Data di pubblicazione: 1999
• Lingua: Inglese
• ISBN 10: 0198503164
• ISBN 13: 9780198503163
• Rilegatura: Copertina rigida
• Numero di pagine: 270
• Redattore: Leslie Ron A., Hunter Jackie, Robertson Harry
• Contatto del produttore: non disponibile
• Persona responsabile: Ufficio Anagrafiche Messaggerie; ufficio.anagrafiche@meli.it; ; Via Verdi, 8; Assago Milano; 20090; Italia