Parkinson's disease has long been perceived as a pure motor disorder, partly due to its initial description by James Parkinson, who suggested that "senses and intellect remain intact", and partly due to the fact that patients with PD did not survive long, before effective treatment became available. As the survival time of patients with Parkinson's disease has substantially increased due to modern treatment, it has become apparent that cognitive deficits and dementia are also frequent features, especially in elderly patients. With the progression of the disease and age, dementia develops in a substantial number of patients and constitutes a major therapeutic challenge. Dementia has thus increasingly been the focus of research and practice in recent years and a large body of knowledge has been accumulated. Despite these developments there has been no single volume dedicated to this topic.
This book provides an extensive overview of the current status of knowledge pertaining to cognitive impairment and dementia associated with Parkinson's disease, intended as a reference book for general neurologists, neurology residents and also those with a special interest in movement disorders. In this edited volume experts in the field describe in detail all aspects of cognitive impairment and dementia in Parkinson's disease, including epidemiology, spectrum of clinical features, pathology, neurochemistry and genetics, findings in auxiliary investigations, relation to other neurodegenerative disorders, diagnostic process and management, and rounded up by discussion of future research directions and expectations. The text is complemented and enriched with tables, figures and heavily referenced to encompass all relevant literature.
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...this book can also be thoroughly recommended to general neurologists ( The Lancet: Neurology)L'autore:
Professor Murat Emre was born in 1956 in Eregli, Turkey. After studying medicine at the Istanbul Faculty of Medicine he trained in Neuroscience and Clinical Neurology at the University of Zürich. He then worked in the fields of neurorehabilitation and clinical research in Switzerland for several years. He trained in movement disorders with Prof. David Marsden at the Queen Square National Hospital for Nervous Diseases, London and in behavioral neurology with Prof. Marsel Mesulam at the Beth Israel Hospital and Harvard Medical School. In 1996 he was appointed as Professor of Neurology at the Istanbul Faculty of Medicine where he started the Behavioral Neurology and Movement Disorders Unit, which he has been chairing since then. His research interests are in Parkinson's disease and related disorders, in particular cognitive aspects of the disease, Alzheimer's disease and related dementias.
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