Apoptosis: The Molecular Biology of Programmed Cell Death (Frontiers in Molecular Biology): 40 - Brossura

Brossura

ISBN 10: 0199638497 ISBN 13: 9780199638499

Casa editrice: Oxford University Press, USA, 2002

Riassunto

Apoptosis is a regulated form of cell demise that can be induced or blocked by groups of specific stimuli. Occurring in all living tissues, it is thought critical to the maintenance of homeostasis and is implicated in lowering susceptibility to tumour growth. Conversely, over-sensitivity to apoptotic triggers can cause cells to be lost inappropriately from tissues, as appears to occur in neurodegenerative diseases. This book examines the molecular pathways regulating apoptosis, progressing from the nematode worm through Drosphila to the more complex pathways evident in mammalian cells. Differences in the cell death pathway within specific tissues are addressed, as are the different genes that may act to regulate progressive steps.

Su questo libro

Recensione

The book is, essentially, a series of reviews of a quality you would expect to find in the top scientific journals. Not only will it prove a good introduction to researchers new to the field, it provides a very useful reference guide to those of us who are not specialists in PCD, but upon whose work the subject often impinges. (Journal of Biological Education)

All the subjects are addressed at just the right level of complexity, with the emphasis on molecular processes involved ... four excellent colour plates. (Journal of Biological Education)

L'autore

Michael Jacobson is at Millennium Pharmaceuticals Inc., Cambridge, MA, USA. Nicola McCarthy is at Division of Cardiovascular Medicine, Addenbrookes Hospital, Cambridge, UK.

Dettagli dell'edizione

• Editore: Oxford University Press, USA
• Data di pubblicazione: 2002
• Lingua: Inglese
• ISBN 10: 0199638497
• ISBN 13: 9780199638499
• Rilegatura: Copertina flessibile
• Numero di pagine: 346
• Redattore: Jacobson Michael, McCarthy Nicola
• Contatto del produttore: non disponibile
• Persona responsabile: Ufficio Anagrafiche Messaggerie; ufficio.anagrafiche@meli.it; ; Via Verdi, 8.; Assago Milano; 20090; Italia