Molecular Biology of RNA

 
9780199671397: Molecular Biology of RNA

RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself.

This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes.

For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research.

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Book Description:

Review from previous edition Highly detailed, and well illustrated, Molecular Biology of RNA represents the first text to address exclusively the role of RNA in biological systems. ( Kevin Coward in Journal of Biological Education, 2012)

This comprehensive textbook is pitched at just the right level and explains the concepts in sufficient detail to make them come to life. ( Ilan Davis in Development, 2011)

Contenuti:

  • 1: Introduction to Molecular Biology of RNA
  • 2: RNA can form versatile structures
  • 3: Catalytic RNAs
  • 4: The RNA-binding proteins
  • 5: Pre-mRNA splicing by the spliceosome
  • 6: Regulated alternative splicing
  • 7: Pre-mRNA splicing defects in development and disease
  • 8: Co-transcriptional pre-mRNA processing
  • 9: Nucleocytoplasmic traffic of messenger RNA
  • 10: Messenger RNA localization
  • 11: Translation of messenger RNA
  • 12: Stability and degradation of mRNA
  • 13: RNA editing
  • 14: The biogenesis and nucleocytoplasmic traffic of non-coding RNAs
  • 15: The 'macro' RNAs: long non-coding RNAs and epigenetics
  • 16: The short non-coding RNAs and gene silencing
  • 17: RNA biology: future perspectives

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

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Elliott, David; Ladomery, Michael
ISBN 10: 0199671397 ISBN 13: 9780199671397
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Descrizione libro Oxford University Press, United Kingdom, 2016. Paperback. Condizione libro: New. 2nd Revised edition. 266 x 201 mm. Language: English . Brand New Book. RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research. Codice libro della libreria AAZ9780199671397

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Descrizione libro Oxford University Press, United Kingdom, 2016. Paperback. Condizione libro: New. 2nd Revised edition. 266 x 201 mm. Language: English . Brand New Book. RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research. Codice libro della libreria AAZ9780199671397

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Descrizione libro Oxford University Press 2015-11-12, Oxford, 2015. paperback. Condizione libro: New. Codice libro della libreria 9780199671397

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Descrizione libro Oxford University Press. Paperback. Condizione libro: new. BRAND NEW, Molecular Biology of RNA (2nd Revised edition), David Elliott, Michael Ladomery, RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research. Codice libro della libreria B9780199671397

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Descrizione libro OUP Oxford 2015-11-01, 2015. Condizione libro: New. Brand new book, sourced directly from publisher. Dispatch time is 24-48 hours from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely. Codice libro della libreria NU-GRD-05269789

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Descrizione libro Oxford University Press, 2016. Condizione libro: New. The versatile RNA molecule, along with its many forms and functions, is elegantly captured in this succinct undergraduate text. Molecular Biology of RNA describes how RNA is not only an intrinsic part of the 'central dogma' of molecular biology, but also plays a part in processes as diverse as the regulation of gene expression and catalysis. Num Pages: 440 pages, Over 300 figures; 8 page colour plate section. BIC Classification: PSAK; PSD. Category: (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 198 x 266 x 22. Weight in Grams: 852. . 2016. 2nd Edition. Paperback. . . . . . Codice libro della libreria V9780199671397

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