Paraneoplastic Syndromes

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9780199772735: Paraneoplastic Syndromes

Paraneoplastic syndromes, defined in this book as "disorders caused by cancer, but not a direct result of cancer invasion of the affected organ or tissue", once believed to be rare and esoteric neurologic disorders have assumed increasing importance as an explanation of neurologic and other symptoms in patients suffered from occult or controllable cancers. This book attempts a comprehensive review of paraneoplastic syndromes from considering both clinical and pathophysiologic aspects. The book is divided into 4 sections: The first is an overview, classifying the disorders, describing a clinical approach to the diagnosis and treatment of paraneoplastic syndromes in general and identifying their pathogenesis. The second section discusses the clinical findings and treatment of individual paraneoplastic syndromes with chapters dedicated to each of the neurologic syndromes and a chapter discussing nonneurologic syndromes such as endocrine, cutaneous, and rheumatologic paraneoplastic disorders. The third section discusses autoantibodies that characterize individual paraneoplastic syndromes. The final section discusses the paraneoplastic syndromes associated with individual cancers.

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

About the Author:

Dr. Darnell studied neurology as Chief Resident with Dr. Fred Plum at The New York Hospital, Cornell, and then, beginning in 1990 and continuing through the present time, with Dr. Jerome Posner at Memorial Sloan-Kettering Cancer Center. Dr. Darnell is currently the Heilbrunn Cancer Professor and Senior Physician at The Rockefeller University and an Investigator with the Howard Hughes Medical Institute, and is an Affiliate Attending Neurologist at Memorial Sloan-Kettering Cancer Center.

Dr. Posner did a Neurology residency at the University of Washington under Dr. Fred Plum. C. Cotzias of Neuro-Oncology at Memorial Sloan-Kettering cancer Center and was recently in only clinical research professor ship from the American Cancer Society.

Contenuti:

  • Contents
  • SECTION 1 OVERVIEW
  • 1. HISTORY
  • DEFINITIONS
  • CLASSIFICATION
  • HISTORY
  • Pathogenesis
  • EPIDEMIOLOGY
  • IMPORTANCE
  • 2. CLINICAL FINDINGS, TREATMENT AND PROGNOSIS
  • INTRODUCTION
  • CLINICAL APPROACH
  • The Patient without Known Cancer The Patient with Known Cancer
  • CLUES TO DIAGNOSIS
  • Clinical Findings Laboratory Investigation
  • PATHOLOGY
  • TREATMENT
  • Plasma Exchange (Plasmapheresis) Intravenous Immunoglobulin
  • Rituximab Cyclophosphamide Corticosteroids Human Chorionic Gonadotropin Recommendations
  • PROGNOSIS
  • 3. PATHOGENESIS
  • INTRODUCTION
  • HISTORICAL VIEWS
  • Toxic Substances Competition for Essential Substrate Bullet Opportunistic Infection Immune Mediated
  • CURRENT CONCEPTS OF PATHOGENESIS
  • Unresolved Questions Conclusions
  • ANIMAL MODELS
  • SECTION 2 CLINICAL SYNDROMES
  • 4. BRAIN (CEREBRUM)
  • INTRODUCTION
  • CEREBRAL CORTEX
  • WHITE MATTER DEMYELINATION
  • BLOOD VESSELS (VASCULITIS)
  • HIPPOCAMPUS/LYMBIC ENCEPHALITIS
  • TASTE

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Darnell MD PhD, Robert B.; Posner MD FAAN, Jerome B.
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Descrizione libro Oxford University Press, 2011. Condizione libro: New. Brand New, Unread Copy in Perfect Condition. A+ Customer Service! Summary: This comprehensive monograph on paraneoplastic syndromes discusses the clinical symptomatology, the diagnosis, the associated autoantibodies and the treatment of individual paraneoplastic syndromes. It emphasizes both the clinical experience of the office and provides an extensive review of the literature. Codice libro della libreria ABE_book_new_0199772738

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Descrizione libro Oxford University Press Inc, United States, 2011. Hardback. Condizione libro: New. 257 x 183 mm. Language: English . Brand New Book. Paraneoplastic syndromes, defined in this book as disorders caused by cancer, but not a direct result of cancer invasion of the affected organ or tissue , once believed to be rare and esoteric neurologic disorders have assumed increasing importance as an explanation of neurologic and other symptoms in patients suffered from occult or controllable cancers. This book attempts a comprehensive review of paraneoplastic syndromes from considering both clinical and pathophysiologic aspects. The book is divided into 4 sections: The first is an overview, classifying the disorders, describing a clinical approach to the diagnosis and treatment of paraneoplastic syndromes in general and identifying their pathogenesis. The second section discusses the clinical findings and treatment of individual paraneoplastic syndromes with chapters dedicated to each of the neurologic syndromes and a chapter discussing nonneurologic syndromes such as endocrine, cutaneous, and rheumatologic paraneoplastic disorders. The third section discusses autoantibodies that characterize individual paraneoplastic syndromes. The final section discusses the paraneoplastic syndromes associated with individual cancers. Codice libro della libreria LIB9780199772735

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Darnell MD PhD, Robert B.; Posner MD FAAN, Jerome B.
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Descrizione libro Oxford University Press Inc, United States, 2011. Hardback. Condizione libro: New. 257 x 183 mm. Language: English . Brand New Book. Paraneoplastic syndromes, defined in this book as disorders caused by cancer, but not a direct result of cancer invasion of the affected organ or tissue , once believed to be rare and esoteric neurologic disorders have assumed increasing importance as an explanation of neurologic and other symptoms in patients suffered from occult or controllable cancers. This book attempts a comprehensive review of paraneoplastic syndromes from considering both clinical and pathophysiologic aspects. The book is divided into 4 sections: The first is an overview, classifying the disorders, describing a clinical approach to the diagnosis and treatment of paraneoplastic syndromes in general and identifying their pathogenesis. The second section discusses the clinical findings and treatment of individual paraneoplastic syndromes with chapters dedicated to each of the neurologic syndromes and a chapter discussing nonneurologic syndromes such as endocrine, cutaneous, and rheumatologic paraneoplastic disorders. The third section discusses autoantibodies that characterize individual paraneoplastic syndromes. The final section discusses the paraneoplastic syndromes associated with individual cancers. Codice libro della libreria LIB9780199772735

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Descrizione libro Oxford University Press Inc. Hardback. Condizione libro: new. BRAND NEW, Paraneoplastic Syndromes, Robert B. Darnell, Jerome B. Posner, Paraneoplastic syndromes, defined in this book as "disorders caused by cancer, but not a direct result of cancer invasion of the affected organ or tissue", once believed to be rare and esoteric neurologic disorders have assumed increasing importance as an explanation of neurologic and other symptoms in patients suffered from occult or controllable cancers. This book attempts a comprehensive review of paraneoplastic syndromes from considering both clinical and pathophysiologic aspects. The book is divided into 4 sections: The first is an overview, classifying the disorders, describing a clinical approach to the diagnosis and treatment of paraneoplastic syndromes in general and identifying their pathogenesis. The second section discusses the clinical findings and treatment of individual paraneoplastic syndromes with chapters dedicated to each of the neurologic syndromes and a chapter discussing nonneurologic syndromes such as endocrine, cutaneous, and rheumatologic paraneoplastic disorders. The third section discusses autoantibodies that characterize individual paraneoplastic syndromes. The final section discusses the paraneoplastic syndromes associated with individual cancers. Codice libro della libreria B9780199772735

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