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Proceedings of an American Chemical Society Carbohydrate Division Symposium (Tohru Ueda Memorial Symposium), held in San Francisco, April 1992. Among the topics in 17 papers: lithiation chemistry of uridine derivatives access to a new anti-HIV-1 lead; approaches to novel isomeric nucleosides as anti
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Contenuti:
Design of New Types of Antitumor Nucleosides (A. Matsuda et al.). Lithiation Chemistry of Uridine Derivatives (H. Tanaka et al.). A Synthesis of 2'Fluoro and 3'FluoroSubstituted Purine Nucleosides via a Direct Approach (K.W. Pankiewicz, K.A. Wantanabe). Allenols Derived from Nucleic Acid Bases-A New Class of AntiHIV Agents (J. Zemlicka). StructureActivity Relationships among HIV Inhibatory, 4'Substituted Nucleosides (E.J. Prisbe et al.). Approaches to Novel Isomeric Nucleosides as Antiviral Agents (V. Nair). Carbocyclic 7Deazaguanosine Nucleosides as Antiviral Agents (S.W. Schneller et al.). Synthesis and Anticancer and Antiviral Activity of Certain Pyramidine Nucleoside Analogues (T.S. Lin, M.C. Liu). Stereocontrolled Routes for the Synthesis of AntiHIV and AntiHBV Nucleosides (J.W. Beach et al.). 5Substituted Arabinofuranosyluracil Nucleosides as Antiherpes Agents (H. Machida, S. Sakata). 6 additional articles. Index.
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Nucleosides And Nucleotides As Antitumor And Antiviral Agents:byBaker, 9780306445200, Springer, Hardcover, Hardcover
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- EditorePlenum Pub Corp
- Data di pubblicazione1993
- ISBN 10 0306445204
- ISBN 13 9780306445200
- RilegaturaCopertina rigida
- Numero di pagine352
- RedattoreBaker David C.
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Descrizione libro Hardcover. Condizione: new. This item is printed on demand. Codice articolo 9780306445200
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Nucleosides and Nucleotides as Antitumor and Antiviral Agents
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Springer US Jul 1993
(1993)
ISBN 10: 0306445204
ISBN 13: 9780306445200
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Descrizione libro Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Due to the worldwide epidemic of acquired immunodeficiency syndrome (AIDS), the past ten years have witnessed a flurry of activity in the chemotherapy of viral diseases. Unprecedented scientific efforts have been made by scientists and clinicians to combat infections of human immunodeficiency virus (HIY), the causative agent. Looking back over the past ten years, we have made remarkable progress toward the treatment of the viral disease: isolation of HIV only two years after the identification of the disease, plus major strides in the areas of the molecular biology and virology of the retrovirus, etc. More remarkably, the discovery of the chemotherapeutic agent AZT (Retrovir) was made within two years after the isolation and identification of the virus, followed by unprecedented drug development efforts to culminate in the FDA approval of AZT in twenty-three months, which was a record-breaking time for approval of any drug for a major disease. The last six to seven years have particularly been an exciting and productive period for nucleoside chemists. Since the activity of AZI' was established in 1985, nucleoside chemists have had golden opportunities to discover additional anti-HIV nucleosipes, which are hoped to be less toxic and more effective than AZT, and the opportunity continues. As we all are aware, AZT possesses extremely potent anti-HIY activity, and no other nucleoside or non nucleoside has surpassed the potency of AZT in vitro. 352 pp. Englisch. Codice articolo 9780306445200
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Nucleosides and Nucleotides as Antitumor and Antiviral Agents: Proceedings of an American Chemical Society Carbohydrate Division Symposium Held in San Francisco, California, April 7, 1992
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Kluwer Academic Publishers Group
(1993)
ISBN 10: 0306445204
ISBN 13: 9780306445200
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Descrizione libro Hardback. Condizione: New. This item is printed on demand. New copy - Usually dispatched within 5-9 working days. Codice articolo C9780306445200
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Nucleosides and Nucleotides as Antitumor and Antiviral Agents
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Descrizione libro Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Due to the worldwide epidemic of acquired immunodeficiency syndrome (AIDS), the past ten years have witnessed a flurry of activity in the chemotherapy of viral diseases. Unprecedented scientific efforts have been made by scientists and clinicians to combat infections of human immunodeficiency virus (HIY), the causative agent. Looking back over the past ten years, we have made remarkable progress toward the treatment of the viral disease: isolation of HIV only two years after the identification of the disease, plus major strides in the areas of the molecular biology and virology of the retrovirus, etc. More remarkably, the discovery of the chemotherapeutic agent AZT (Retrovir) was made within two years after the isolation and identification of the virus, followed by unprecedented drug development efforts to culminate in the FDA approval of AZT in twenty-three months, which was a record-breaking time for approval of any drug for a major disease. The last six to seven years have particularly been an exciting and productive period for nucleoside chemists. Since the activity of AZI' was established in 1985, nucleoside chemists have had golden opportunities to discover additional anti-HIV nucleosipes, which are hoped to be less toxic and more effective than AZT, and the opportunity continues. As we all are aware, AZT possesses extremely potent anti-HIY activity, and no other nucleoside or non nucleoside has surpassed the potency of AZT in vitro. Codice articolo 9780306445200
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Nucleosides and Nucleotides as Antitumor and Antiviral Agents
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(1993)
ISBN 10: 0306445204
ISBN 13: 9780306445200
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Descrizione libro Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Due to the worldwide epidemic of acquired immunodeficiency syndrome (AIDS), the past ten years have witnessed a flurry of activity in the chemotherapy of viral diseases. Unprecedented scientific efforts have been made by scientists and clinicians to combat . Codice articolo 458416741
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NUCLEOSIDES AND NUCLEOTIDES AS A
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Descrizione libro Condizione: New. New. In shrink wrap. Looks like an interesting title! 1.8. Codice articolo Q-0306445204
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