Synthetic DNA Delivery Systems: 7 - Rilegato

 
9780306477010: Synthetic DNA Delivery Systems: 7
Rilegato
ISBN 10: 0306477017 ISBN 13: 9780306477010
Casa editrice: Springer-Verlag GmbH, 2003

Sinossi

DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function.

Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest.

Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides and polypeptides as DNA delivery systems and self-assembled delivery systems based on cationic lipids and polymers are discussed. Targeted delivery to organelles, tumor cells and dendritic cells comprise an important topic.

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Contenuti

I: Introduction; D. Luo, W.M. Saltzman.
II: Overcoming Cellular Barriers along the DNA Delivery Pathway. Outside of the cell: Supramolar assemblies of DNA delivery systems; Pitard. At the cell surface: Engineering the surface properties of synthetic gene delivery systems; Schaffer. Inside of the cell: Histidine containing peptides and polypeptides as nucleic acid vectors; Midoux. Intracellular targets for DNA delivery: nuclei and mitochondria; Torchilin.
III: Targeted DNA Delivery. Immune cells: Mannose receptor-mediated gene delivery into antigen presenting dendritic cells; Zenke. Muscle: Electro-gene-transfer: a new approach for muscle gene delivery; Toniatti. Tumor: Tumor-targeted gene transfer with DNA polyplexes; Wagner.
IV: Novel DNA Delivery Systems. Light: Photochemical transfection: a technology for efficient light directed gene delivery; Hogset. Ultrasound: Sonoportation: mechanical DNA delivery by ultrasonic cavitation; Miller, Greenleaf.

Product Description

Book by Luo Dan

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
Springer-Verlag GmbH
Data di pubblicazione
2003
Lingua
Inglese
ISBN 10 
0306477017
ISBN 13 
9780306477010
Rilegatura
Copertina rigida
Numero di pagine
152
Redattore
Saltzman W. Mark, Luo Dan
Contatto del produttore
non disponibile
Persona responsabile
Springer Nature Customer Service Center GmbH
ProductSafety@springernature.com

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