Presenting a unique balance between science and clinical relevance, this new text is a concise, well-illustrated overview of immunology for students. Focusing on what medical students need to know, it fills the niche for a reader-friendly, patient-oriented text in this challenging field. Clinical boxes include real patient scenarios, making the textbook interesting and relevant. Experimental detail is kept to a minimum, used only where it helps the student understand difficult concepts. It also provides a superb review of major components in immunological interaction: important molecules, specific immune response and role of innate response in complementing specific response, and immunity to microbes.
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Section I
Introduction
1. Basic concepts and components of the immune system
2. Basic components
Section II
Antigen-recognition molecules
3. Introduction to antigens and recognition
4. Antigens and antibody structure
5. Antibody-antigen interaction
6. Antibody diversity
7. The T cell receptor
8. Major histocompatility complex
9. Review of antigen recognition
Section III
Physiology
10. Antigen processing and presentation
11. Lymphocyte activation
12. Haematopoiesis
13. The organs and tissue of the immune system
14. B cell development
15. T cell development
16. Cell-cell interaction in generating effector lymphocytes
17. Immunological memory
18. Review of immune physiology
Section IV
Innate immunity
19. Constitutive defenses including complement
20. Phagocytes
21. Killing in the immune system
22. Inflammation
23. Review of innate immunity
Section V
Immune system in health and disease
24. Infections and vaccines
25. Hypersensitivity reactions
26. Immediate hypersensitivity (type I): allergy
27. Autoimmunity
28. Antibody-mediated hypersensitivity (type II)
29. Immune complex disease (type III hypersensitivity)
30. Delayed hypersensitivity (type IV)
31. Primary immunodeficiency
32. Secondary immunodeficiency
33. Transplantation
34. Tumor immunology
35. Integration of the immune system with other regulatory systems
36. Review of immunity in health and disease
Index
Book by Nairn PhD Roderick Helbert FRCP FRCPath PhD Matt
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