Handbook of Transcranial Magnetic Stimulation

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9780340720097: Handbook of Transcranial Magnetic Stimulation

Transcranial Magnetic Stimul0tion (TMS) is a non-invasive technique that has revolutionised the study of the human nervous system allowing in-depth investigations of complex voluntary motor control pathways. Today, many of the techniques used in TMS have become routine in clinical electrophysiological assessments. As an investigative tool, its application ranges from clinical diagnostics to cognitive research. Now the use of repetitive TMS (rTMS) is gaining support amongst psychiatrists as evidence suggests that it may provide an alternative to ECT in treating depression and other psychiatric disorders.

This handbook brings together the basic science, fundamental principles, and essential procedures of TMS needed by all those useing or planning to use the technique clinically or in research. The final two sections focus upon current up to date knowledge of applications of the technique. Written in a digestible style by world authorities in different related specialties, the Handbook of TMS will be a valuable and comprehensive guide for clinical neurophysiologists, neuropsychiatrists, neurologists and psychiatrists.

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Provides the most comprehensive coverage of transcranial magnetic stimulation now available.
Journal of Neurology, Neurosurgery and Psychiatry


Part 1 Basic Principles
The history and basic principles of magnetic nerve stimulation
Physical principles for TMS
Principles of magnetic stimulator design
Safety and side effects of TMS and rTMS
Ethical issues
Part 2 Methods
Basic physiology of transcranial magnetic stimulation
Basic physiology of peripheral and spinal cord magnetic stimulation
Effects of rTMS on immediate early gene expression
Central conduction time studies
Motor threshold, facilitation and silent period in cortical m.s.
Single motor unit recording
Mapping studies
Paired pulse techniques
Callosal Fibre Function
Imaging of brain before, during and after magnetic stimulation
Part 3 Clinical Applications
Introduction to diagnostic strategies
Peripheral and cranial nerves
Intraoperative spinal cord motor path monitoring
Spinal cord injury
Longitudinal study of central motor conduction delay
Development of the corticospinal tract
Multiple sclerosis and peripheral neuropathies
TMS in movement disorders
The application of TMS in studying central motor fatigue
Part 4 Cognitive Functions
Memory and the use of TMS in learning and research
Eye movements
Mood and emotion
Reaction times
Neuroplasticity and transcranial magnetic stimulation
Part 5 Psychiatric Disorders: does TMS affect cortical function
Transcranial magnetic stimulation and electroconvulsive therapy
The use of TMS in major psych

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