Handbook of Single-Molecule Biophysics - Rilegato

Rilegato

ISBN 10: 0387764968 ISBN 13: 9780387764962

Casa editrice: Springer-Verlag GmbH, 2009

Riassunto

During the last decade, a number of novel biophysical methods have been developed that allow the manipulation and study of individual biomolecules. The ability to monitor biological processes at the fundamental level of sensitivity, that of a single molecule, has given rise to an improved understanding of the underlying molecular mechanisms. Through the removal of ensemble averaging, distributions and fluctuations of molecular properties can be characterized, transient intermediates identified, and catalytic mechanisms elucidated. By applying forces on biomolecules while monitoring their activity, important information can be obtained on how proteins couple function to structure. The Handbook of Single-Molecule Biophysics provides an introduction to these techniques and presents an extensive discussion of the new biological insights obtained from them.

Editorial Advisory Board: Daniel Müller, Cheng Zhu, Claus Seidel, Xiaowei Zhuang, Thomas Schmidt, Nynke Dekker.

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Dalla quarta di copertina

The last decade has seen the development of a number of novel biophysical methods that allow the manipulation and study of individual biomolecules. The ability to monitor biological processes at this fundamental level of sensitivity has given rise to an improved understanding of the underlying molecular mechanisms. Through the removal of ensemble averaging, distributions and fluctuations of molecular properties can be characterized, transient intermediates identified, and catalytic mechanisms elucidated. By applying forces on biomolecules while monitoring their activity, important information can be obtained on how proteins couple function to structure. The Handbook of Single-Molecule Biophysics provides an introduction to these techniques and presents an extensive discussion of the new biological insights obtained from them. Coverage includes:

• Experimental techniques to monitor and manipulate individual biomolecules
• The use of single-molecule techniques in super-resolution and functional imaging
• Single-molecule studies of physical properties of biomolecules
• Single-molecule enzymology and biochemistry
• Single molecules in the membrane
• Single-molecule techniques in living cells
• Integration of single-molecule biophysics and nanoscience

Dettagli dell'edizione

• Editore: Springer-Verlag GmbH
• Data di pubblicazione: 2009
• Lingua: Inglese
• ISBN 10: 0387764968
• ISBN 13: 9780387764962
• Rilegatura: Copertina rigida
• Numero di pagine: 652
• Redattore: Oijen Antoine Van, Hinterdorfer Peter
• Contatto del produttore: non disponibile
• Persona responsabile: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3,69115 Heidelberg, Germany; Heidelberg; 69115; Germania