Hematology: Basic Principles and Practice - Rilegato

Rilegato

ISBN 10: 0443066620 ISBN 13: 9780443066627

Casa editrice: Churchill Livingstone, 2003

Riassunto

The fourth edition of this leading text reflects the new direction and growth of the field of hematology as an academic and clinical discipline. Both a state-of-the-art website and a critically acclaimed reference.

• THE WEBSITE:
• Incorporates the text with a state-of-the-art, dedicated website...featuring fully searchable contents of the 4TH Edition.
• Patient information sheets.
• Includes all of the artwork from the text downloadable into PowerPoint presentations.
• Features weekly content updates Edited by Dr. Hoffman.
• THE BOOK:
• Full color throughout for the first time (color figures in place!)
• The definitive, complete reference resource for hematologic disorders provides "one-stop shopping" for information; appeals to both practitioners and researchers
• Red "opinion" boxes contain treatment strategies and recommendations by the experts
• Clinically oriented focus
• Includes more than 15 new chapters

Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

Su questo libro

Contenuti

Part I. MOLECULAR AND CELLULAR BASIS OF HEMATOLOGY
Chapter 1: Anatomy and Physiology of the Gene
Chapter 2: Genomic Approaches to the Study of Hematologic Science
Chapter 3: Protein Synthesis, Processing, and Degradation
Chapter 4: Protein Architecture: Relationship of Form and Function
Chapter 5: Regulation of Cellular Response
Chapter 6: Cell Adhesion
Chapter 7: Control of Cell Division
Chapter 8: Cell Death
Chapter 9: Pharmacogenomics and Hematological Diseases
Part II. IMMUNOLOGIC BASIS OF HEMATOLOGY
Chapter 10: Overview and Compartmentalization of the Immune System
Chapter 11: B-Cell Development
Chapter 12: T-Cell and NK-Cell Immunity
Chapter 13: Dendritic Cell Biology
Chapter 14: Regulation of Activation of B and I Lymphocytes
Chapter 15: Leukocyte Trafficking
Chapter 16: Tolerance and Autoimmunity
Part III. BIOLOGY OF STEM CELLS AND DISORDERS OF HEMATOPOIESIS
Chapter 17: Stem Cell Model of Hematopoiesis
Chapter 18: Bone Marrow Microenvironment
Chapter 19: The Humeral Regulation of Hematopoiesis
Chapter 20: Biology of Erythropoiesis, Erythroid Differentiation, and Maturation
Chapter 21: Granulopoiesis and Monocytopoiesis
Chapter 22: Thrombocytopoiesis
Chapter 23: Thrombocytopenia Due to Decreased Platelet Production
Chapter 24: Inherited Forms of Bone Marrow Failure
Chapter 25: Aplastic Anemia
Chapter 26: Paroxysmal Nocturnal Hemoglobinuria
Chapter 27: Pure Red Cell Aplasia
Part IV. RED BLOOD CELLS
Chapter 28: Pathobiology of the Human Erythrocyte and Its Hemoglobins
Chapter 29: Approach to Anemia in the Adult and Child
Chapter 30: Anemia of Chronic Diseases
Chapter 31: Pathology of Iron Metabolism
Chapter 32: Disorders of Iron Metabolism: Iron Deficiency and Overload
Chapter 33: Heme Biosynthesis and Its Disorders: Porphyrias and Sideroblastic Anemias
Chapter 34: Megablastic Anemias
Chapter 35: Thalassemia Syndromes
Chapter 36: Pathology of Sickle Cell Disease
Chapter 37: Sickle Cell Disease
Chapter 38: Hemoglobin Variants Associated with Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias
Chapter 39: Red Cell Enzymopathies
Chapter 40: Red Cell Membrane Disorders
Chapter 41: Autoimmune Hemolytic Anemias
Chapter 42: Extrinsic Nonimmune Hemolytic Anemias
Part V. HOST DEFENSE AND ITS DISORDERS
Chapter 43: Complement Biology and Immunoglobulin
Chapter 44: Normal Phagocyte Structure and Function
Chapter 45: Eosinophilia, Eosinophil-Associated Diseases, Chronic Eosinophil Leukemia, and the Hypereosinophilic Syndromes
Chapter 46: Disorders of Phagocyte Function and Number
Chapter 47: Disorders of Lymphocyte Function
Chapter 48: Histiocytic Disorders
Chapter 49: Lysosomal Storage Diseases: Perspective and Principles
Chapter 50 Infectious Mononucleosis and Other Epstein-Barr Virus-Associated Diseases
Chapter 51: The Spleen and Its Disorders
Chapter 52: Basophils, Mast Cells, and Systemic Mastocytosis
Part VI. HEMATOLOGIC MALIGNANCIES
Chapter 53: Conventional Cytogenetics and Molecular Cytogenetics in Hematological Malignancies
Chapter 54: The Molecular Basis of Neoplasia
Chapter 55: Pharmacology and Molecular Mechanisms of Antineoplastic Agents for Hematologic Malignancies
Chapter 56: Radiation Therapy in the Treatment of Hematologic Malignancies
Chapter 57: Clinical Use of Hematopoietic Growth Factors
Chapter 58: Radioimmunotherapy for B-Cell and Non-Hodgkin Lymphoma
Chapter 59: Pathobiology of Acute Myeloid Leukemia
Chapter 60: Clinical Manifestations of Acute Myeloid Leukemia
Chapter 61: Therapy for Acute Myeloid Leukemia
Chapter 62: Acute Myeloid Leukemia in Children
Chapter 63: Pathobiology of Acute Lymphoblastic Leukemia
Chapter 64: Clinical Manifestations of Acute Lymphoblastic Leukemia
Chapter 65: Treatment of Childhood Acute Lymphoblastic Leukemia
Chapter 66: Acute Lymphoblastic Leukemia in Adults
Chapter 67: Myelodysplastic Syndrome: Biology and Treatment
Chapter 68: Polycythemia Vera
Chapter 69: Chronic Myeloid Leukemia
Chapter 70: Myelofibrosis with Myeloid Metaplasia
Chapter 71: Essential Thrombocythemia
Chapter 72: Myelodysplastic Syndromes and Myeloproliferative Syndromes in Children
Chapter 73: Pathobiology of Non-Hodgkin Lymphomas
Chapter 74: Patho-Biology of Hodgkin's Lymphoma
Chapter 75: Hodgkin's Disease: Clinical Manifestations, Staging, and Therapy
Chapter 76: The Pathologic Basis for the Classification of Non-Hodgkin Lymphomas
Chapter 77: Clinical Manifestations, Staging, and Treatment of Non-Hodgkin Lymphoma
Chapter 78: Malignant Lymphomas in Childhood
Chapter 79: Chronic Lymphocytic Leukemia
Chapter 80: Hairy Cell Leukemia
Chapter 81: Cutaneous T-Cell Lymphomas
Chapter 82: AIDS-Related Lymphomas
Chapter 83: Multiple Myeloma and Other Plasma Cell Disorders
Chapter 84: Immunoglobulin Light Chain Amyloidosis (Primary Amyloidosis, AL)
Chapter 85: Atypical Immune Lymphoproliferations
Chapter 86: Clinical Approaches to Infections in the Compromised Host
Chapter 87: Nutritional Support of Patients with Hematologic Malignancies
Chapter 88: Psychosocial Aspects of Hematologic Disorders
Chapter 89: Pain Management and Antiemetic Therapy in Hematologic Disorders
Chapter 90: Palliative Care
Chapter 91: Indwelling Access Devices
Chapter 92: Late Complications of Hematologic Diseases and Their Therapies
Part VII. TRANSPLANTATION
Chapter 93: Hematopoietic Stem Cell Transplantation for Acquired Nonmalignant Diseases and Myelodysplastic Syndrome
Chapter 94: Hematopoietic Cell Transplant for Immune Deficiences and Genetic Diseases
Chapter 95: Results of Allogeneic Hematopoietic Cell Transplant for Hematologic Malignancies
Chapter 96: Autologous Transplant for Hematologic malignancies and Solio Tumors
Chapter 97: Unrelated Donor Stem Cell Transplantation Therapy Anasetti
Chapter 98: Umbilical Cord Blood Transplantation
Chapter 99: Preparative Regimens for Hematopoietic Cell Transplantation
Chapter 100: Graft-versus-Host Disease and Graft-versus-Leukemia
Chapter 101: Graft Engineering to Enhance Engraftment, Reduce Graft-versus-Host Disease and Provide a Graft-versus-Tumor Effect
Chapter 102: Gene Transfer for Hematologic Disorders
Chapter 103: Experimental Cell Therapy
Chapter 104: Complications After Hematopoietic Cell Transplantation
Part VIII. HEMOSTASIS AND THROMBOSIS
Chapter 105: Megakaryocyte and Platelet Structure
Chapter 106: The Molecular Basis for Platelet Function
Chapter 107: The Molecular Basis for Platelet Activation
Chapter 108: The Blood Vessel Wall
Chapter 109: Molecular Basis of Blood Coagulation
Chapter 110: Molecular and Cellular Basis of Fibrinolysis
Chapter 111: Regulatory Mechanisms in Hemostasis: Natural Anticoagulants
Chapter 112: Clinical Evaluation of Hemorrhagic Disorders: Bleeding History and Differential Diagnosis of Pupura
Chapter 113: Laboratory Evaluation of Hemostatic Disorders
Chapter 114: Structure, Biology, and Genetics of Factor VIII
Chapter 115: Biochemistry of Factor IX and Molecular Biology of Hemophilia B
Chapter 116: Clinical Aspects and Therapy of Hemophilia
Chapter 117: Inhibitors in Hemophilia
Chapter 118: Other Clotting Factor Deficiencies
Chapter 119: Disorders of Fibrinogen
Chapter 120: Structure, Biology, and Genetics of von Willebrand Factor
Chapter 121: von Willebrand Disease: Clinical Aspects and Therapy
Chapter 122: Vitamin K: Metabolism and Disorders
Chapter 123: Inhibitors of Blood Coagulation
Chapter 124: Disseminated Intrvascular Coagulation
Chapter 125: Hemostatic Defects Associated with Dysproteinemias
Chapter 126: Disorders of Coagulation in the Neonate
Chapter 127: Hypercoagulable States
Chapter 128: Venous Thromboembolism
Chapter 129: Arterial Thromboembolism
Chapter 130: Anticoagulation and Thrombolytic Therapy
Chapter 131: Immune Thrombocytopenic Purpura, Neonatal Alloimmune Thrombocytopenia, and Posttransfusion Purpura
Chapter 132: Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndrome
Chapter 133: Thrombocytopenia Due to Platelet Destruction and Hypersplenism
Chapter 134: Hereditary Disorders of Platelet Function
Chapter 135: Acquired Disorders of Platelet Function
Part IX. TRANSFUSION MEDICINE
Chapter 136: Human Blood Group Anitgens and Antibodies - Part 1: Carbohydrate Determinants - Part 2: Protein Determinants
Chapter 137: Human Platelet Antigens
Chapter 138: Human Leukocyte Antigen (HLA) and Human Neutrophil Antigen (HNA) Systems
Chapter 139: Principles of Red Blood Cell Transfusion
Chapter 140: Principles of Platelet Transfusion Therapy
Chapter 141: Principles of Neutrophil (Granulocyte) Transfusions
Chapter 142: Transfusion of Plasma Derivatives: Fresh-Frozen Plasma, Cryoprecipitate, Albumin, and Immunoglobulins
Chapter 143: Preparation of Plasma-Derived and Recombinant Human Plasma Proteins
Chapter 144: Transfusion Therapy for Coagulation factor Deficiencies
Chapter 145: Hemapheresis and Cellular Therapy
Chapter 146: Practical Aspects of Stem Cell Collection
Chapter 147: Transfusion Reactions
Chapter 148: Transfusion-Transmitted Diseases
Chapter 149: Transfusion Medicine in Hematopoietic Stem Cell and Solid Organ Transplantation
Chapter 150: Red Blood Cell Substitutes
Part X. CONSULTATIVE HEMATOLOGY
Chapter 151: Hematologic Manifestations of Systemic Disease: Liver and Renal Disease
Chapter 152: Hematologic Manifestations of Systemic Disease: Infection, Chronic Inflammation, and Cancer
Chapter 153: Hematologic Manifestations of AIDS
Chapter 154: Hematologic Problems in the Surgical Patient: Bleeding and Thrombosis
Chapter 155: Hematologic Aspects of Pregnancy
Chapter 156: Hematologic Manifestations of Childhood Illness
Part XI. SPECIAL TESTS AND PROCEDURES
Chapter 157: Bone Marrow Examination
Chapter 158: Automated Analysis of Blood Cells
Ch...

Product Description

Book by Hoffman MD Ronald Benz Jr MD Edward J Shattil MD S

Dettagli dell?edizione

• Editore: Churchill Livingstone
• Data di pubblicazione: 2003
• ISBN 10: 0443066620
• ISBN 13: 9780443066627
• Rilegatura: Copertina rigida
• Lingua: Inglese
• Numero edizione: 4
• Numero di pagine: 2864
• Redattore: Hoffman Ronald, Benz Edward J., Shattil Sanford J.
• Contatto del produttore: non disponibile