In a relatively short period, Dynamic Combinatorial Chemistry (DCC) has grown from proof-of-concept experiments in a few isolated labs to a broad conceptual framework with applications to an exceptional range of problems in molecular recognition, lead compound identification, catalyst design, nanotechnology, polymer science, and others. Bringing together a group of respected experts, this overview explains how chemists can apply DCC and fragment-based library methods to lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science.
Chapters cover:
Basic theory
Approaches to binding in proteins and nucleic acids
Molecular recognition
Self-sorting
Catalyst discovery
Materials discovery
Analytical chemistry challenges
A comprehensive, single-source reference about DCC methods and applications including aspects of fragment-based drug discovery, this is a core reference that will spark the development of new solutions and strategies for chemists building structure libraries and designing compounds and materials.
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Descrizione libro Condizione: New. pp. x + 265 Index 1st Edition. Codice articolo 26577024
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Descrizione libro Condizione: New. Codice articolo 4248465-n
Descrizione libro Hardcover. Condizione: new. Hardcover. Effective techniques for applying Dynamic Combinatorial Chemistry In a relatively short period, Dynamic Combinatorial Chemistry (DCC) has grown from proof-of-concept experiments in a few isolated labs to a broad conceptual framework with applications to an exceptional range of problems in molecular recognition, lead compound identification, catalyst design, nanotechnology, polymer science, and others. Bringing together a group of respected experts, this overview explains how chemists can apply DCC and fragment-based library methods to lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science. Chapters cover: Basic theory Approaches to binding in proteins and nucleic acids Molecular recognition Self-sorting Catalyst discovery Materials discovery Analytical chemistry challenges A comprehensive, single-source reference about DCC methods and applications including aspects of fragment-based drug discovery, this is a core reference that will spark the development of new solutions and strategies for chemists building structure libraries and designing compounds and materials. This book presents an overview of dynamic combinatorial chemistry (DCC) and fragment-based library methods and how chemists apply them to the problems of lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Codice articolo 9780470096031
Descrizione libro Condizione: New. This book presents an overview of dynamic combinatorial chemistry (DCC) and fragment-based library methods and how chemists apply them to the problems of lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science. Editor(s): Miller, Benjamin L. Num Pages: 266 pages, Illustrations. BIC Classification: PN; TG. Category: (P) Professional & Vocational. Dimension: 244 x 166 x 18. Weight in Grams: 512. . 2009. 1st Edition. Hardcover. . . . . Codice articolo V9780470096031