The Organic Chemists' Companion provides a practical, hands-on resource for students and practitioners of organic synthesis. It presents the fundamentals and guides the reader through the entire process of organic synthesis. It includes basic instructions on everything from on handling reagents, gases, and solvents to conducting and working up/purifying reactions as well as applying analytical techniques to identify the reaction product.* Packed with data and practical tips and organized for quick reference* Includes guidelines for literature searches to help readers find additional information* Features colour photos, drawings, charts, graphs, and tables to complement the information* Includes real-life examples showing how to apply the information.
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Descrizione libro Wiley-Interscience, 2007. Paperback. Condizione libro: New. Codice libro della libreria P110470107073
Descrizione libro Wiley-Interscience, 2007. Paperback. Condizione libro: New. book. Codice libro della libreria 0470107073
Descrizione libro Wiley-Interscience, 2007. Condizione libro: New. Brand New, Unread Copy in Perfect Condition. A+ Customer Service! Summary: Preface. Acknowledgments. 1. Searching the Literature. 1.1. Commercial availability. 1.2. Literature preparations. 2. Reagents. 2.1. Short path distillation. 2.2. Ampules. 2.3. Reagent solutions. 2.4. Titration. 2.5. Reagent storage. 2.6. Subtle reagent variations. 2.7. Dangerous reagents. 2.8. Reagent properties. 3. Gases. 3.1. Lecture bottles. 3.2. Tanks or cylinders. 3.3. Gas safety. 4. Reactions on a Small Scale - 1-25 mmol. 4.1. Reaction flasks. 4.2. Stirring. 4.3. Glass joints. 4.4. Inert atmosphere. 4.5. Apparatus for addition. 4.6. Condensers. 4.7. Other equipment and considerations. 5. Temperature Control. 5.1. Heating. 5.2. Cooling. 6. Solvents. 6.1. Selection. 6.2. Purity. 6.3. Degassing. 6.4. Ammonia. 7. The Research Notebook. 8. Conducting the Reaction Itself. 8.1. Reagents supplied as dispersions. 8.2. Azeotropic drying. 8.3. Stoichiometry. 8.4. Syringe and inert atmosphere techniques. 8.5. General procedure for transfer of materials by syringe. 8.6. Addition. 8.7. Special techniques. 8.7.1.Water removal. 8.7.2.Reactions above atmospheric pressure. 8.7.3.Reagent gases. 8.7.4.Ultrasonication. 8.8 Quenching . 8.9. Specialized reagents. 8.9.1. Diazomethane. 8.9.2. Lithium aluminum hydride. 8.9.3.Hydrogen peroxide. 8.10. Reaction time vs. purification time. 9. Following the Reaction. 9.1. Thin layer chromatography (TLC). 9.1.1. Cutting glass TLC plates. 9.1.2. Spotting TLC plates. 9.1.3. Eluting TLC plates. 9.1.4. Visualizing TLC plates. 9.2. Gas chromatography (GC). 9.3. High pressure liquid chromatography (HPLC). 9.4. NMR spectroscopy. 10. Working Up Reactions. 10.1. Solvent extracation. 10.2. Drying organic solutions. 10.3. Specialized work-ups. 10.3.1. Reactions producing triphenylphosphine oxide. 10.3.2. Reactions involving boron compounds. 10.3.3. Reactions involving copper salts. 10.3.4. Reactions involving aluminum reagents. 10.3.5. Reactions involving tin reagents. 11. Evaporation. 12. Vacuum Systems. 12.1. Vacuum sources. 12.2. Vacuum manifolds. 12.3. Vacuum gauges. 13. Purification of Products. 13.1. Distillation. 13.2. Silica gel chromatography. 13.3. Flash column chromatography. 13.4. Gradients. 13.5. Special absorbents. 13.5.1. Triethylamine-treated silica gel. 13.5.2. Oxalic acid-coated silica gel. 13.5.3. Silver nitrate-impregnated silica gel. 13.5.4. Other sorbents. 13.6. Preparative gas chromatography. 14. Methods for Structure Elucidation. 14.1. Nuclear magnetic resonance spectroscopy. 14.2. Infrared spectroscopy (IR). 14.3. Ultravilolet spectroscopy (UV). 14.4. Combustion analysis. 14.5. Mass spectrometry. 14.6. Crystallography. 15. Cleaning Up After the Reaction. 16. Specific Examples. 16.1. The experimental. 16.2. The Org. Syn. Prep. 16.3. Comparison. 17. Strategies for Reaction Organization. Appendices. 1. NMR spectral data of common contaminants of organic reaction products. 2. Synthetic solvent selection chart. 3. Recipes for TLC stains. 4. Mixotropic series. 5. Stuck joints. 6. Acidities of organic functional groups. 7. Aciditie. Codice libro della libreria ABE_book_new_0470107073