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9780470193419: Guide to Fluorine NMR for Organic Chemists
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AN UNPARALLELED ONE-STOP GUIDE TO FLUORINE NMR

Guide to Fluorine NMR for Organic Chemists provides a unique single source on both fluorine NMR and the impact of fluorine substituents on proton and carbon NMR spectra. Helping working chemists overcome the challenges associated with the synthetic methodologies of fluorinated compounds, this guide enables the effective use of these increasingly popular spectroscopic techniques to accurately characterize compounds that contain fluorine.

Following a thorough introduction of fluorinated compounds, chapters in the text cover:

  • An overview of fluorine NMR

  • The single fluorine substituent

  • The CF2 group

  • The trifluoromethyl group

  • More heavily fluorinated compounds

  • Compounds and substituents with fluorine directly bound to heteroatoms

With unparalleled depth and completeness, the coverage ranges from those compounds containing only a few fluorinated substituents, typically employed in pharmaceutical and agricultural applications, to more heavily fluorinated compounds.

Featuring NMR data for more than 1,000 specific compunds and including more than 100 exemplary spectra, Guide to Fluorine NMR for Organic Chemists gives the working chemist and advanced student an essential tool for understanding cutting-edge NMR techniques and interpreting the resulting spectroscopic data.

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Recensione:
"I just picked up a copy of ... "Guide to Fluorine NMR for Organic Chemists" and I just wanted to email you and let you know that it′s a great book! Some of my research group are biochemists/chemists interested in making and using novel fluorinated amino acids, some of these compounds finding their way into protein research. I have placed [the] book in the lab for their use, which has helped them in their spectroscopic analysis of their compounds...."
Dr. John F. Honek, University of Waterloo

"[The book] helped with some complicated fluoroarene compounds we are working with.  I particularly like the concentrated treatment for the CF2 group – that has to be the most data in one place on the topic. I also liked explaining why there is non–first–order behavior, not just that there is.    Thanks again for a very useful book."
Dr. Carl Busacca, Boehringer Ingelheim Pharmaceuticals

"I just finished reading the first two chapters [the] book .  it is just what my students and I have been needing."
Dr. Stephen Warren, Gonzaga University

L'autore:
William R. Dolbier, Jr., is the Col. Allen R. and Margaret G. Crow Professor of Chemistry at the University of Florida. He received his BS in chemistry from Stetson University in 1961 and his PhD in organic chemistry from Cornell University in 1965. Following a postdoctoral appointment at Yale University, he joined the faculty at the University of Florida in 1966. Professor Dolbier was the recipient of the 2000 American Chemical Society (ACS) Award for Creative Work in Fluorine Chemistry, and is a past member of the Executive Committee of the Fluorine Division of the ACS.

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  • EditoreJohn Wiley & Sons Inc
  • Data di pubblicazione2009
  • ISBN 10 0470193417
  • ISBN 13 9780470193419
  • RilegaturaCopertina rigida
  • Numero edizione1
  • Numero di pagine256

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