Dabrowiak, James C. Metals in Medicine

ISBN 13: 9780470681978

Metals in Medicine

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9780470681978: Metals in Medicine

Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts applicable to metallo-drugs and their biological targets, interactions that exist between the agents and substances in the biological milieu, basic pharmacokinetic and pharmacodynamic properties including transport and uptake of drugs by the cells, and methods for measuring efficacy and toxicity of agents. The steps from drug discovery to market place are also briefly outlined and discussed. These chapters lay the groundwork, in order that students can clearly understand how agents work, whatever their subject background. Following this introduction, chapters focus on individual metallo-drugs and agents for treating and detecting disease, their synthesis, structure and general properties, known mechanism of action and important physical and chemical principles that apply. Topics covered include cisplatin; platinum anticancer drugs; ruthenium, titanium, and gallium for treating cancer; gold compounds for treating arthritis, cancer, and other diseases; vanadium, copper, and zinc in medicine; metal complexes for diagnosing disease; and metals in nanomedicine. Throughout the book, "Feature Boxes" expand on features of drugs that are not directly related to studying metals in medicine, for example discovery, medical use, specialist assays, and metals in biology. At the end of the chapters there are specifically designed problems/exercises that apply basic kinetic, thermodynamic and chemical principles to practical problem solving in metals in medicine. Metals in Medicine distils the essence of this important topic for undergraduate and graduate students in chemistry, biochemistry, biology and the related areas of biophysics, pharmacology, and bioengineering, and for researchers in other fields interested in getting a general insight into metals in medicine.

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James C. Dabrowiak
Editore: John Wiley and Sons Ltd, United States (2010)
ISBN 10: 0470681977 ISBN 13: 9780470681978
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Descrizione libro John Wiley and Sons Ltd, United States, 2010. Paperback. Condizione libro: New. 244 x 188 mm. Language: English . Brand New Book. Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts applicable to metallo-drugs and their biological targets, interactions that exist between the agents and substances in the biological milieu, basic pharmacokinetic and pharmacodynamic properties including transport and uptake of drugs by the cells, and methods for measuring efficacy and toxicity of agents. The steps from drug discovery to market place are also briefly outlined and discussed. These chapters lay the groundwork, in order that students can clearly understand how agents work, whatever their subject background. Following this introduction, chapters focus on individual metallo-drugs and agents for treating and detecting disease, their synthesis, structure and general properties, known mechanism of action and important physical and chemical principles that apply. Topics covered include cisplatin; platinum anticancer drugs; ruthenium, titanium, and gallium for treating cancer; gold compounds for treating arthritis, cancer, and other diseases; vanadium, copper, and zinc in medicine; metal complexes for diagnosing disease; and metals in nanomedicine. Throughout the book, Feature Boxes expand on features of drugs that are not directly related to studying metals in medicine, for example discovery, medical use, specialist assays, and metals in biology. At the end of the chapters there are specifically designed problems/exercises that apply basic kinetic, thermodynamic and chemical principles to practical problem solving in metals in medicine. Metals in Medicine distils the essence of this important topic for undergraduate and graduate students in chemistry, biochemistry, biology and the related areas of biophysics, pharmacology, and bioengineering, and for researchers in other fields interested in getting a general insight into metals in medicine. Codice libro della libreria AAH9780470681978

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ISBN 10: 0470681977 ISBN 13: 9780470681978
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Descrizione libro Wileyand#8211;Blackwell, 2009. PAP. Condizione libro: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Codice libro della libreria FW-9780470681978

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James C. Dabrowiak
Editore: John Wiley and Sons Ltd, United States (2010)
ISBN 10: 0470681977 ISBN 13: 9780470681978
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Descrizione libro John Wiley and Sons Ltd, United States, 2010. Paperback. Condizione libro: New. 244 x 188 mm. Language: English . Brand New Book. Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts applicable to metallo-drugs and their biological targets, interactions that exist between the agents and substances in the biological milieu, basic pharmacokinetic and pharmacodynamic properties including transport and uptake of drugs by the cells, and methods for measuring efficacy and toxicity of agents. The steps from drug discovery to market place are also briefly outlined and discussed. These chapters lay the groundwork, in order that students can clearly understand how agents work, whatever their subject background. Following this introduction, chapters focus on individual metallo-drugs and agents for treating and detecting disease, their synthesis, structure and general properties, known mechanism of action and important physical and chemical principles that apply. Topics covered include cisplatin; platinum anticancer drugs; ruthenium, titanium, and gallium for treating cancer; gold compounds for treating arthritis, cancer, and other diseases; vanadium, copper, and zinc in medicine; metal complexes for diagnosing disease; and metals in nanomedicine. Throughout the book, Feature Boxes expand on features of drugs that are not directly related to studying metals in medicine, for example discovery, medical use, specialist assays, and metals in biology. At the end of the chapters there are specifically designed problems/exercises that apply basic kinetic, thermodynamic and chemical principles to practical problem solving in metals in medicine. Metals in Medicine distils the essence of this important topic for undergraduate and graduate students in chemistry, biochemistry, biology and the related areas of biophysics, pharmacology, and bioengineering, and for researchers in other fields interested in getting a general insight into metals in medicine. Codice libro della libreria AAH9780470681978

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James C. Dabrowiak
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Descrizione libro Wiley, 2009. Paperback. Condizione libro: New. 1. Codice libro della libreria DADAX0470681977

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ISBN 10: 0470681977 ISBN 13: 9780470681978
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Descrizione libro 2009. Paperback. Condizione libro: NEW. 9780470681978 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Codice libro della libreria HTANDREE0773618

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Descrizione libro Wiley, 2009. Paperback. Condizione libro: New. book. Codice libro della libreria 0470681977

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Descrizione libro John Wiley & Sons Inc, 2010. Paperback. Condizione libro: Brand New. 1st edition. 334 pages. 9.50x7.50x0.75 inches. In Stock. Codice libro della libreria __0470681977

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Descrizione libro Wiley, 2009. Paperback. Condizione libro: New. Codice libro della libreria P110470681977

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Descrizione libro 2009. Paperback. Condizione libro: New. 1st. 192mm x 244mm x 18mm. Paperback. Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts.Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. 334 pages. 0.610. Codice libro della libreria 9780470681978

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James C. Dabrowiak
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ISBN 10: 0470681977 ISBN 13: 9780470681978
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Descrizione libro Wiley#8211;Blackwell, 2009. Paperback. Condizione libro: New. 19 x 24.3 cm. Our orders are sent from our warehouse locally or directly from our international distributors to allow us to offer you the best possible price and delivery time. Book. Codice libro della libreria MM-60132659

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