Molecular Pharmacology: From DNA to Drug Discovery

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9780470684436: Molecular Pharmacology: From DNA to Drug Discovery

This textbook provides a fresh, comprehensive and accessibleintroduction to the rapidly expanding field of molecularpharmacology. Adopting a drug target-based, rather than thetraditional organ/system based, approach this innovative guidereflects the current advances and research trend towards molecularbased drug design, derived from a detailed understanding ofchemical responses in the body. Drugs are then tailored to fit atreatment profile, rather than the traditional method of trial and error drug discovery which focuses ontesting chemicals on animals or cell cultures and matching theireffects to treatments.

Providing an invaluable resource for advanced under-graduate andMSc/PhD students, new researchers to the field and practitionersfor continuing professional development, MolecularPharmacology explores; recent advances and developments in thefour major human drug target families (G-protein coupled receptors,ion channels, nuclear receptors and transporters), cloning of drugtargets, transgenic animal technology, gene therapy,pharmacogenomics and looks at the role of calcium in the cell. * Current - focuses on cutting edge techniques andapproaches, including new methods to quantify biological activitiesin different systems and ways to interpret and understandpharmacological data. * Cutting Edge - highlights advances in pharmacogenomicsand explores how an individual s genetic makeup influencestheir response to therapeutic drugs and the potential for harmfulside effects. * Applied - includes numerous, real-world examples and adetailed case-study based chapter which looks at current andpossible future treatment strategies for cystic fibrosis. This casestudy considers the relative merits of both drug therapy forspecific classes of mutation and gene therapy to correct theunderlying defect. * Accessible - contains a comprehensive glossary,suggestions for further reading at the end of each chapter and anassociated website that provides a complete set of figures fromwithin the book.

A companion website with additional resources is available atwww.wiley.com/go/dickenson/dnamolecular

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John Dickenson, Chris Lloyd Mills, Christian Thode
Editore: John Wiley and Sons Ltd, United States (2013)
ISBN 10: 0470684437 ISBN 13: 9780470684436
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Descrizione libro John Wiley and Sons Ltd, United States, 2013. Paperback. Condizione libro: New. 1. Auflage. 244 x 188 mm. Language: English . Brand New Book. This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of trial and error drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. *Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. *Cutting Edge - highlights advances in pharmacogenomics and explores how an individual s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. *Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. *Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book. A companion website with additional resources is available at. Codice libro della libreria AAH9780470684436

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John Dickenson, Chris Lloyd Mills, Christian Thode
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ISBN 10: 0470684437 ISBN 13: 9780470684436
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Descrizione libro John Wiley and Sons Ltd 2012-12-19, Hoboken, 2012. paperback. Condizione libro: New. Codice libro della libreria 9780470684436

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John Dickenson, Chris Lloyd Mills, Christian Thode
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Descrizione libro John Wiley and Sons Ltd, United States, 2013. Paperback. Condizione libro: New. 1. Auflage. 244 x 188 mm. Language: English . Brand New Book. This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of trial and error drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. *Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. *Cutting Edge - highlights advances in pharmacogenomics and explores how an individual s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. *Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. *Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book. A companion website with additional resources is available at. Codice libro della libreria AAH9780470684436

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Descrizione libro Wileyand#8211;Blackwell, 2012. PAP. Condizione libro: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Codice libro della libreria FW-9780470684436

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John Dickenson, Fiona Freeman, Chris Lloyd Mills, Christian Thode, Shiva Sivasubramaniam
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Descrizione libro Wiley-Blackwell 2012-12-19, 2012. Condizione libro: New. Brand new book, sourced directly from publisher. Dispatch time is 24-48 hours from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely. Codice libro della libreria NU-LBR-01149758

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Descrizione libro 2012. Paperback. Condizione libro: New. 1st. 190mm x 244mm x 19mm. Paperback. This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditiona.Shipping may be from multiple locations in the US or from the UK, depending on stock availability. 424 pages. 0.920. Codice libro della libreria 9780470684436

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Dickenson, John; Freeman, Fiona; Lloyd Mills, Chris; Thode, Christian; Sivasubramaniam, Shiva
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Descrizione libro Wiley John + Sons, 2012. Condizione libro: New. Codice libro della libreria L9780470684436

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Descrizione libro Wiley John & Sons Dez 2012, 2012. Taschenbuch. Condizione libro: Neu. 246x189x14 mm. Neuware - This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of 'trial and error' drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. 424 pp. Englisch. Codice libro della libreria 9780470684436

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Descrizione libro 2012. Paperback. Condizione libro: NEW. 9780470684436 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Codice libro della libreria HTANDREE0784587

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John Dickenson (Nottingham Trent University ); Chris Lloyd Mills (Nottingham Trent University); Christian Thode (Nottingham Trent University); Fiona Freeman (Nottingham Trent University); Shiva Sivasubramaniam (Nottingham Trent University); Mark G. D
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Descrizione libro John Wiley and Sons. Condizione libro: New. Brand New. Codice libro della libreria 0470684437

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