Molecular Pharmacology: From DNA to Drug Discovery

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9780470684436: Molecular Pharmacology: From DNA to Drug Discovery

This textbook provides a fresh, comprehensive and accessibleintroduction to the rapidly expanding field of molecularpharmacology. Adopting a drug target-based, rather than thetraditional organ/system based, approach this innovative guidereflects the current advances and research trend towards molecularbased drug design, derived from a detailed understanding ofchemical responses in the body. Drugs are then tailored to fit atreatment profile, rather than the traditional method of trial and error drug discovery which focuses ontesting chemicals on animals or cell cultures and matching theireffects to treatments.

Providing an invaluable resource for advanced under-graduate andMSc/PhD students, new researchers to the field and practitionersfor continuing professional development, MolecularPharmacology explores; recent advances and developments in thefour major human drug target families (G-protein coupled receptors,ion channels, nuclear receptors and transporters), cloning of drugtargets, transgenic animal technology, gene therapy,pharmacogenomics and looks at the role of calcium in the cell. * Current - focuses on cutting edge techniques andapproaches, including new methods to quantify biological activitiesin different systems and ways to interpret and understandpharmacological data. * Cutting Edge - highlights advances in pharmacogenomicsand explores how an individual s genetic makeup influencestheir response to therapeutic drugs and the potential for harmfulside effects. * Applied - includes numerous, real-world examples and adetailed case-study based chapter which looks at current andpossible future treatment strategies for cystic fibrosis. This casestudy considers the relative merits of both drug therapy forspecific classes of mutation and gene therapy to correct theunderlying defect. * Accessible - contains a comprehensive glossary,suggestions for further reading at the end of each chapter and anassociated website that provides a complete set of figures fromwithin the book.

A companion website with additional resources is available atwww.wiley.com/go/dickenson/dnamolecular

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Dickenson, John; Freeman, Fiona; Mills, Chris Lloyd; Sivasubramaniam, Shiva; Thode, Christian
ISBN 10: 0470684437 ISBN 13: 9780470684436
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Descrizione libro Condizione libro: New. Codice libro della libreria 6232946-n

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Dickenson, John; Freeman, Fiona; Mills, Chris Lloyd; Sivasubramaniam, Shiva; Thode, Christian
Editore: John Wiley and Sons Ltd, United States (2013)
ISBN 10: 0470684437 ISBN 13: 9780470684436
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Descrizione libro John Wiley and Sons Ltd, United States, 2013. Paperback. Condizione libro: New. 1. Auflage. 244 x 188 mm. Language: English . Brand New Book. This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of trial and error drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. *Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. *Cutting Edge - highlights advances in pharmacogenomics and explores how an individual s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. *Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. *Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book. A companion website with additional resources is available at. Codice libro della libreria AAZ9780470684436

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Dickenson, John; Freeman, Fiona; Mills, Chris Lloyd; Sivasubramaniam, Shiva; Thode, Christian
Editore: John Wiley and Sons Ltd, United States (2013)
ISBN 10: 0470684437 ISBN 13: 9780470684436
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Descrizione libro John Wiley and Sons Ltd, United States, 2013. Paperback. Condizione libro: New. 1. Auflage. 244 x 188 mm. Language: English . Brand New Book. This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of trial and error drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. *Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. *Cutting Edge - highlights advances in pharmacogenomics and explores how an individual s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. *Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. *Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book. A companion website with additional resources is available at. Codice libro della libreria AAZ9780470684436

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Dickenson, John; Freeman, Fiona; Mills, Chris Lloyd; Sivasubramaniam, Shiva; Thode, Christian
Editore: John Wiley and Sons Ltd 2012-12-19, Hoboken (2012)
ISBN 10: 0470684437 ISBN 13: 9780470684436
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Descrizione libro John Wiley and Sons Ltd 2012-12-19, Hoboken, 2012. paperback. Condizione libro: New. Codice libro della libreria 9780470684436

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Dickenson, John; Freeman, Fiona; Mills, Chris Lloyd; Sivasubramaniam, Shiva; Thode, Christian
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Descrizione libro Condizione libro: New. Bookseller Inventory # ST0470684437. Codice libro della libreria ST0470684437

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Dickenson, John; Freeman, Fiona; Mills, Chris Lloyd; Sivasubramaniam, Shiva; Thode, Christian
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Descrizione libro Wileyand#8211;Blackwell, 2012. PAP. Condizione libro: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Codice libro della libreria FW-9780470684436

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Dickenson, John; Freeman, Fiona; Mills, Chris Lloyd; Sivasubramaniam, Shiva; Thode, Christian
Editore: John Wiley and Sons Ltd (2013)
ISBN 10: 0470684437 ISBN 13: 9780470684436
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Descrizione libro John Wiley and Sons Ltd, 2013. Condizione libro: New. 2013. 1st Edition. Paperback. Provides an introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based approach, this book reflects the advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Num Pages: 424 pages, illustrations. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 191 x 246 x 21. Weight in Grams: 908. . . . . . . Codice libro della libreria V9780470684436

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Dickenson, John; Freeman, Fiona; Mills, Chris Lloyd; Sivasubramaniam, Shiva; Thode, Christian
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Descrizione libro Paperback. Condizione libro: New. Not Signed; This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards mo. book. Codice libro della libreria ria9780470684436_rkm

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Dickenson, John; Freeman, Fiona; Mills, Chris Lloyd; Sivasubramaniam, Shiva; Thode, Christian
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Descrizione libro Wiley-Blackwell, 2012. Paperback. Condizione libro: New. Brand New Book. Shipping: Once your order has been confirmed and payment received, your order will then be processed. The book will be located by our staff, packaged and despatched to you as quickly as possible. From time to time, items get mislaid en route. If your item fails to arrive, please contact us first. We will endeavour to trace the item for you and where necessary, replace or refund the item. Please do not leave negative feedback without contacting us first. All orders will be dispatched within two working days. If you have any quesions please contact us. Codice libro della libreria V9780470684436

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Dickenson, John; Freeman, Fiona; Mills, Chris Lloyd; Sivasubramaniam, Shiva; Thode, Christian
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Descrizione libro Wiley-Blackwell 2012-12-19, 2012. Condizione libro: New. Brand new book, sourced directly from publisher. Dispatch time is 24-48 hours from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely. Codice libro della libreria NU-LBR-01149758

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