Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood

Valutazione media 0
( su 0 valutazioni fornite da Goodreads )
 
9780470686683: Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood

Human blood performs many important functions including defence against disease and transport of biomolecules, but perhaps the most important is to carry oxygen – the fundamental biochemical fuel - and other blood gases around the cardiovascular system. Traditional therapies for the impairment of this function, or the rapid replacement of lost blood, have centred around blood transfusions. However scientists are developing chemicals (oxygen therapeutics, or “blood substitutes”) which have the same oxygen-carrying capability as blood and can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired.

Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood links the underlying biochemical principles of the field with chemical and biotechnological innovations and pre-clinical development.

The first part of the book deals with the chemistry, biochemistry, physiology and toxicity of oxygen, including chapters on hemoglobin reactivity and regulation; the major cellular and physiological control mechanisms of blood flow and oxygen delivery;  hemoglobin and myoglobin;  nitric oxide and oxygen; and the role of reactive oxygen and nitrogen species in ischemia/reperfusion Injury.

The book then discusses medical needs for oxygen supply, including acute traumatic hemorrhage and anemia; diagnosis and treatment of haemorrhages in "non-surgical" patients; management of perioperative bleeding; oxygenation in the preterm neonate; ischemia

normobaric and hyperbaric oxygen therapy for ischemic stroke and other neurological conditions; and transfusion therapy in β thalassemia and sickle cell disease

Finally “old”and new strategies for oxygen supply are described. These include the political, administrative and logistic issues surrounding transfusion;  conscientious objection in patient blood management; causes and consequences of red cell incompatibility; biochemistry of red blood cell storage;  proteomic investigations on stored red blood cells; red blood cells from stem cells; the universal red blood cell;  allosteric effectors of hemoglobin; hemoglobin-based oxygen carriers;  oxygen delivery by natural and artificial oxygen carriers; cross-linked and polymerized hemoglobins as potential blood substitutes; design of novel pegylated hemoglobins as oxygen carrying plasma expanders; hb octamers by introduction of surface cysteines; hemoglobin-vesicles as a cellular type hemoglobin-based oxygen carrier; animal models and oxidative biomarkers to evaluate pre-clinical safety of extracellular hemoglobins; and academia – industry collaboration in blood substitute development.

Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood is an essential reference for clinicians, haematologists, medicinal chemists, biochemists, molecular biologists, biotechnologists and blood substitute researchers.

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

I migliori risultati di ricerca su AbeBooks

1.

Editore: John Wiley and Sons Ltd, United States (2011)
ISBN 10: 0470686685 ISBN 13: 9780470686683
Nuovi Rilegato Quantità: 10
Da
The Book Depository US
(London, Regno Unito)
Valutazione libreria
[?]

Descrizione libro John Wiley and Sons Ltd, United States, 2011. Hardback. Condizione libro: New. Language: English . Brand New Book. Scientists are developing oxygen therapeutics, or blood substitutes, with the same oxygen-carrying capability as blood, that can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired. This book links the underlying biochemical principles of the field with chemical and biotechnological innovations and pre-clinical development, starting with the observation that an oxygen therapeutic agent can be developed only upon a deep understanding of oxygen and nitric oxide, homeostasis and regulation, and the well-documented correlations between adverse effects of a specific product and its biochemical-physiological properties. Codice libro della libreria AAH9780470686683

Maggiori informazioni su questa libreria | Fare una domanda alla libreria

Compra nuovo
EUR 121,01
Convertire valuta

Aggiungere al carrello

Spese di spedizione: GRATIS
Da: Regno Unito a: U.S.A.
Destinazione, tempi e costi

2.

Editore: Wiley (2011)
ISBN 10: 0470686685 ISBN 13: 9780470686683
Nuovi Rilegato Quantità: 1
Da
Irish Booksellers
(Rumford, ME, U.S.A.)
Valutazione libreria
[?]

Descrizione libro Wiley, 2011. Hardcover. Condizione libro: New. book. Codice libro della libreria 0470686685

Maggiori informazioni su questa libreria | Fare una domanda alla libreria

Compra nuovo
EUR 121,02
Convertire valuta

Aggiungere al carrello

Spese di spedizione: GRATIS
In U.S.A.
Destinazione, tempi e costi

3.

Editore: John Wiley and Sons Ltd, United States (2011)
ISBN 10: 0470686685 ISBN 13: 9780470686683
Nuovi Rilegato Quantità: 10
Da
The Book Depository
(London, Regno Unito)
Valutazione libreria
[?]

Descrizione libro John Wiley and Sons Ltd, United States, 2011. Hardback. Condizione libro: New. Language: English . Brand New Book. Scientists are developing oxygen therapeutics, or blood substitutes, with the same oxygen-carrying capability as blood, that can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired. This book links the underlying biochemical principles of the field with chemical and biotechnological innovations and pre-clinical development, starting with the observation that an oxygen therapeutic agent can be developed only upon a deep understanding of oxygen and nitric oxide, homeostasis and regulation, and the well-documented correlations between adverse effects of a specific product and its biochemical-physiological properties. Codice libro della libreria AAH9780470686683

Maggiori informazioni su questa libreria | Fare una domanda alla libreria

Compra nuovo
EUR 127,32
Convertire valuta

Aggiungere al carrello

Spese di spedizione: GRATIS
Da: Regno Unito a: U.S.A.
Destinazione, tempi e costi

4.

Andrea Mozzarelli, Stefano Bettati
Editore: John Wiley and Sons Ltd
ISBN 10: 0470686685 ISBN 13: 9780470686683
Nuovi Rilegato Quantità: > 20
Da
THE SAINT BOOKSTORE
(Southport, Regno Unito)
Valutazione libreria
[?]

Descrizione libro John Wiley and Sons Ltd. Hardback. Condizione libro: new. BRAND NEW, Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood, Andrea Mozzarelli, Stefano Bettati, Scientists are developing oxygen therapeutics, or "blood substitutes," with the same oxygen-carrying capability as blood, that can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired. This book links the underlying biochemical principles of the field with chemical and biotechnological innovations and pre-clinical development, starting with the observation that an oxygen therapeutic agent can be developed only upon a deep understanding of oxygen and nitric oxide, homeostasis and regulation, and the well-documented correlations between adverse effects of a specific product and its biochemical-physiological properties. Codice libro della libreria B9780470686683

Maggiori informazioni su questa libreria | Fare una domanda alla libreria

Compra nuovo
EUR 124,17
Convertire valuta

Aggiungere al carrello

Spese di spedizione: EUR 7,78
Da: Regno Unito a: U.S.A.
Destinazione, tempi e costi

5.

Andrea Mozzarelli (University of Parma); Stefano Bettati (University of Parma)
Editore: John Wiley and Sons
ISBN 10: 0470686685 ISBN 13: 9780470686683
Nuovi Quantità: > 20
Da
INDOO
(Avenel, NJ, U.S.A.)
Valutazione libreria
[?]

Descrizione libro John Wiley and Sons. Condizione libro: New. Brand New. Codice libro della libreria 0470686685

Maggiori informazioni su questa libreria | Fare una domanda alla libreria

Compra nuovo
EUR 137,01
Convertire valuta

Aggiungere al carrello

Spese di spedizione: EUR 3,01
In U.S.A.
Destinazione, tempi e costi

6.

ANDREA MOZZARELLI
ISBN 10: 0470686685 ISBN 13: 9780470686683
Nuovi Rilegato Quantità: 10
Da
Herb Tandree Philosophy Books
(Stroud, GLOS, Regno Unito)
Valutazione libreria
[?]

Descrizione libro 2011. Hardback. Condizione libro: NEW. 9780470686683 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Codice libro della libreria HTANDREE0779832

Maggiori informazioni su questa libreria | Fare una domanda alla libreria

Compra nuovo
EUR 171,56
Convertire valuta

Aggiungere al carrello

Spese di spedizione: EUR 8,95
Da: Regno Unito a: U.S.A.
Destinazione, tempi e costi

7.

Editore: John Wiley and Sons Ltd, United States (2011)
ISBN 10: 0470686685 ISBN 13: 9780470686683
Nuovi Rilegato Quantità: 10
Da
Book Depository hard to find
(London, Regno Unito)
Valutazione libreria
[?]

Descrizione libro John Wiley and Sons Ltd, United States, 2011. Hardback. Condizione libro: New. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. Scientists are developing oxygen therapeutics, or blood substitutes, with the same oxygen-carrying capability as blood, that can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired. This book links the underlying biochemical principles of the field with chemical and biotechnological innovations and pre-clinical development, starting with the observation that an oxygen therapeutic agent can be developed only upon a deep understanding of oxygen and nitric oxide, homeostasis and regulation, and the well-documented correlations between adverse effects of a specific product and its biochemical-physiological properties. Codice libro della libreria BZV9780470686683

Maggiori informazioni su questa libreria | Fare una domanda alla libreria

Compra nuovo
EUR 184,79
Convertire valuta

Aggiungere al carrello

Spese di spedizione: GRATIS
Da: Regno Unito a: U.S.A.
Destinazione, tempi e costi

8.

Mozzarelli, Andrea/ Bettati, Stefano
Editore: John Wiley & Sons Inc (2011)
ISBN 10: 0470686685 ISBN 13: 9780470686683
Nuovi Rilegato Quantità: 2
Da
Revaluation Books
(Exeter, Regno Unito)
Valutazione libreria
[?]

Descrizione libro John Wiley & Sons Inc, 2011. Hardcover. Condizione libro: Brand New. 1st edition. 466 pages. 9.92x6.85x1.18 inches. In Stock. Codice libro della libreria __0470686685

Maggiori informazioni su questa libreria | Fare una domanda alla libreria

Compra nuovo
EUR 178,74
Convertire valuta

Aggiungere al carrello

Spese di spedizione: EUR 6,72
Da: Regno Unito a: U.S.A.
Destinazione, tempi e costi