Organic Synthesis: The Disconnection Approach,2nd Edition introduces this important technique,to help students to design their own organic syntheses. There areforty chapters: those on the synthesis of given types of moleculesalternate with strategy chapters in which the methods just learntare placed in a wider context. The synthesis chapters cover manyways of making each type of molecule starting with simple aromaticand aliphatic compounds with one functional group and progressingto molecules with many functional groups. The strategy chapterscover questions of selectivity, protection, stereochemistry, anddevelop more advanced thinking via reagents specifically designedfor difficult problems.
Examples are drawn from pharmaceuticals, agrochemicals, naturalproducts, pheromones, perfumery and flavouring compounds,dyestuffs, monomers, and intermediates used in more advancedsynthetic work. Reasons for wishing to synthesise each compound aregiven.
This second edition has been fully revised and updated with amodern look. Recent examples and techniques are included andillustrated additional material has been added to take the studentto the level required by the sequel, “Organic Synthesis:Strategy and Control”.
Several chapters contain extensive new material based on coursesthat the authors give to chemists in the pharmaceuticalindustry.
Organic Synthesis: The Disconnection Approach, 2ndedition provides a full course in retrosynthetic analysis forchemistry and biochemistry students and a refresher for organicchemists working in industry and academia.
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?This book is suitable for advanced undergraduate students, researchers and professional chemists. Both the writing and the diagrams are simple and clear.? ( Reviews, May 2009)
Dr Stuart Warren, Department of Chemistry, University of Cambridge, UK
Dr Warren is the author of the bestselling textbooks Organic Synthesis: The Disconnection Approach (Wiley), Organic Synthesis: Strategy and Control (Wiley) and Organic Chemistry (OUP).
Dr Paul Wyatt, School of Chemistry, University of Bristol, UK
Dr Wyatt is Director of Undergraduate Studies for the School of Chemistry at Bristol University and also Director of BRISTOL ChemLabS - a HEFCE Centre for Excellence in Teaching & Learning. He is co-author, with Warren, of Organic Synthesis: Strategy and Control.
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Descrizione libro hardback. Condizione: New. Language: ENG. Codice articolo 9780470712375
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Descrizione libro Gebunden. Condizione: New. Organic Synthesis: The Disconnection Approach is the long-awaited second edition of a classic textbook the first to provide a structured course in retrosynthesis- now an important technique used by generations of organic chemists. Now fully revised and upd. Codice articolo 556557805
Descrizione libro Condizione: New. One approach to organic synthesis is retrosynthetic analysis. With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. Num Pages: 342 pages, Illustrations. BIC Classification: PNN. Category: (P) Professional & Vocational. Dimension: 256 x 196 x 25. Weight in Grams: 838. . 2008. 2nd. Hardcover. . . . . Codice articolo V9780470712375
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