Articoli correlati a Non-Reproductive Actions of Sex Steroids: No. 191
Sinossi
Prominent clinicians and researchers from diverse disciplines discuss the basic cell and molecular biology of steroid action and sex steroids' effects on the nervous and immune systems. Provides an integrated evaluation of the advantages and disadvantages of hormone replacement therapy.
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Dalla quarta di copertina
Sex steroids have a number of physiological effects in addition to their classical sex-related roles. This book brings together clinicians and basic researchers from a number of disciplines to discuss the non-reproductive actions of sex steroids. In many instances, sex steroids mediate the expression of a variety of genes by influencing the activity of intracellular receptors, which in turn bind to hormone response elements in the promoters of hormone-regulated genes. Direct membrane-mediated effects have also been described. Sex steroids have numerous effects on the brain, and although many of these are directed to neural functions underlying reproduction, others are more broadly related to brain function. Among these are effects on cognitive function, motor coordination (high levels of oestrogen exacerbate symptoms of Parkinson?s disease), depressive illness and dementia (oestrogen has been shown to improve cognitive function in Alzheimer?s disease patients). Neurosteroids also have an important role in nerve repair. The protective role of oestrogen against cardiovascular disease in women is widely documented: the mechanism behind this cardioprotective effect is discussed. The incidence of autoimmune disease is higher in women than in men, and oestradiol appears to exacerbate the symptoms of many of these diseases, with the exception of rheumatoid arthritis, where oestrogen suppresses symptoms. The effects of sex steroids on the immune system are therefore covered in the book. Sex steroids have been implicated in the pathogenesis of several types of cancers. Synthetic steroid antagonists, such as tamoxifen, have been widely studied as therapeutic agents for hormone-dependent cancers. Hormone replacement therapy (HRT) has been shown to have a number of beneficial effects. In particular, HRT reduces postmenopausal demineralization of bone, thus slowing the advance of osteoporosis. Protective effects of HRT on cardiovascular disease have also been reported. The advantages and disadvantages of HRT therefore form a major topic of discussion in the book.
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Book by CIBA Foundation Symposium
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- EditoreJohn Wiley & Son Ltd
- Data di pubblicazione1995
- ISBN 10 0471955132
- ISBN 13 9780471955139
- RilegaturaCopertina flessibile
- Numero di pagine350
- RedattoreGoode Jamie A.
Compra usato
Condizioni: ottimoAncien livre de bibliothèque. Edition... Scopri di più su questo articolo
EUR 3,14
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EUR 8,00
Da: Francia a: U.S.A.
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Non-Reproductive Actions of Sex Steroids
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John Wiley & Sons Ltd, 1995
ISBN 10: 0471955132
ISBN 13: 9780471955139
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Softcover. Condizione: Très bon. Ancien livre de bibliothèque. Edition 1995. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Former library book. Edition 1995. Ammareal gives back up to 15% of this item's net price to charity organizations. Codice articolo E-411-263
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Non-Reproductive Actions of Sex Steroids.; (Ciba Foundation Symposium 191.)
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Non-Reproductive Actions of Sex Steroids (Ciba Foundation Symposia)
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Condizione: good. Befriedigend/Good: Durchschnittlich erhaltenes Buch bzw. Schutzumschlag mit Gebrauchsspuren, aber vollständigen Seiten. / Describes the average WORN book or dust jacket that has all the pages present. Codice articolo M00471955132-G
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Non-Reproductive Actions of Sex Steroids (Ciba Foundation Symposia)
Editore:
John Wiley & Sons Ltd, 1995
ISBN 10: 0471955132
ISBN 13: 9780471955139
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Brossura
Da: Buchpark, Trebbin, Germania
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Condizione: Gut. Zustand: Gut - Gebrauchs- und Lagerspuren. Außen: verschmutzt, angestoßen. | Seiten: 350 | Sprache: Englisch | Produktart: Bücher. Codice articolo 42670851/3
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NonReproductive Actions of Sex Steroids.
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New York: Wiley, 1995
ISBN 10: 0471955132
ISBN 13: 9780471955139
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Da: Plurabelle Books Ltd, Cambridge, Regno Unito
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Hardback. Condizione: As New. Series: Novartis Foundation Symposia. ix 308p sturdy hardback, glossy laminated navy covers, like new condition, no significant wear, firm binding and sharp corners, pages clean and bright, free from annotation and highlighting, an excellent copy Language: English Weight (g): 630. Codice articolo 234502
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