Drug Resistance in the Treatment of Cancer - Rilegato

Pinedo, Herbert M.; Giaccone, Giuseppe

Rilegato

ISBN 10: 0521473217 ISBN 13: 9780521473217

Casa editrice: Cambridge University Press, 1998

Riassunto

The development of drug-resistant cancers is considered to be the most significant obstacle to the cure of cancer today. Nearly half of all patients with cancer suffer from tumours that are intrinsically resistant to chemotherapy, and most of the remaining half develop drug resistance during the course of their treatment. This book reviews the mechanisms and clinical implications of drug resistance in cancer with unrivalled authority. Chapters cover topics of current clinical concern, including multiple drug resistance and its reversal, topoisomerase drugs, apoptosis, dose intensity and escalation, gene therapy and haematopoietic support. The authors are among the leading clinicians and investigators in the field. These authoritative volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the applications of biomedical science to the understanding and management of cancer.

Su questo libro

Recensione:

'... recommended for clinical oncologists, who will find extensive information on this topic which is seldom to be found in oncology textbooks.' Annals of Oncology

'The strength of the book is related to the weaknesses described above. Multiple knowledgeable authors review topics related to drug resistance. Some of the authors primarily review their own work, while others try and update the reader on significant contributions from others. The book accomplishes what it is supposed to; it provides a way for the reader to learn and somewhat update his/her knowledge of drug resistance.' Howard Bailey, Madison, Wisconsin

Descrizione del libro:

Reviews the mechanisms and clinical implications of drug resistance in cancer, considered to be the most significant obstacle to the cure of cancer today. Topics covered include multiple drug resistance and its reversal, topoisomerase drugs, apoptosis, dose intensity and escalation, gene therapy and haematopoietic support.

Su questa edizione

• Editore: Cambridge University Press
• Data di pubblicazione: 1998
• ISBN 10: 0521473217
• ISBN 13: 9780521473217
• Rilegatura: Copertina rigida
• Numero di pagine: 340