Contenuti:
Preface. Part I: Molecular Biology of Relaxation. 1. Overview: the Molecular Phenotype of Normal and Impaired Relaxation; K. Schwartz, K.R. Boheler. 2. Regulation of Gene Expression in the Failing Myocardium: Evidence for a Heart Failure Gene Program; A.M. Feldman, V.T. Edwards, J.E. Lawrence, W.D. Rosenblum, R.E. Williams. 3. Sarcoplasmic Reticulum Gene Expression in Human Heart Failure; M. Periasamy, M. Arai. 4. Molecular Aspects of the Control of Myocardial Relaxation; I. Shiojima, I. Komuro, T. Yamazaki, R. Nagai, Y. Yazaki. 5. Molecular Physiology of Ventricular Hypertrophy; K.R. Chien. Part II: Consequences of Altered Gene Expression: the Economy of Diastole. 6. Regulatory Proteins and Diastolic Relaxation; R.J. Solaro, B.M. Wolska, M. Westfall. 7. Intracellular Free Calcium in Hypertrophy and Failure; J.K. Gwathmey, R. Liao, R.J. Hajjar. 8. A Molecular Biophysical Approach to Contraction and Relaxation; N.R. Alpert, J.N. Peterson. 9. On the Relations among ATP Hydrolysis, Cation Accumulation and Diastolic Dysfunction; M. Bernard, S. Neubauer, J.S. Ingwall. 10. Adrenergic Signal Transduction in Congestive Heart Failure: Effects on Diastole; J.D. Marsh. 11. The Cardiac Renin-Angiotensin System in Cardiac Hypertrophy and Failure; B.H. Lorell. 12. Altered Force-Frequency Relation and Excitation-Contraction Coupling in the Failing Human Heart. Relevance of SR-Ca2+-ATPase Protein Levels; G. Hasenfuss, H. Reinecke, R. Studer, H. Drexler, B. Peiske, C. Holubarsch, H. Holtz, N.R. Alpert, H. Just. Part III: Impaired Relaxation in Experimental Models: Ischemia and Hypoxia. 13. Effects of Hypoxia and Ischemia on Intracellular Calcium and Relaxation: Studies in the Aequorin-Loaded Whole Heart Model; J.P. Morgan, K. Harada, A. Meissner, C. Williams, H.P. Carrozza, L.A. Bentivegna, Y. Kihara, W. Grossman. 14. Diastolic Dysfunction during Ischemia: Role of Glycolytic ATP Generation; C.S. Apstein. 15. Does Calcium Overload Adequately Explain Diastolic Dysfunction during Metabolic Inhibition? W.H. Barry, H. Ikenouchi. 16. Mechanisms of Relaxation: Perspectives from Studies in Single Cardiac Cells; E.G. Lakatta, S.J. Sollott, A.M. Janczewski, G. Gambassi, H.W. Silverman, M.C. Capogrossi, R.S. Danziger, H.A. Spurgeon. 17. Modulation of Diastolic Dysfunction in the Intact Heart; W.C. Little, Che-Ping Cheng. 18. Altered Load: an Important Component of Impaired Diastolic Function in Hypertension and Heart Failure; R.P. Shannon, K. Komamura, R.J. Gelpi, S.F. Vatner. 19. Endothelial-Ventricular Interaction in Normal and Diseased Hearts; D.L. Brutsaert, S.U. Sys, T.C. Gillebert, A.F. Leite-Moreira. Part IV: Impaired Relaxation in Experimental Models: Hypertrophy and Failure. 20. Diastolic Dysfunction in Experimental Heart Failure; S. Sasayama, H. Asanoi, S. Ishizaka, Y. Kihara. 21. Interplay of Hypertrophy and Myocardial Ischemia; S. Isoyama. 22. Myocardial Fibrosis: Structural Basis for Diastolic Dysfunction; K.T. Weber, S.E. Campbell, C.G. Brilla, J.S. Janicki. 23. Coronary Venous Pressure and Left Ventricular Diastolic Distensibility; W. Grossman,
Product Description:
Book by None
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.