Molecular Diagnosis and Treatment of Melanoma - Rilegato

Kirkwood, John M.

Rilegato

ISBN 10: 082470102X ISBN 13: 9780824701024

Casa editrice: CRC Press, 1998

Riassunto

Facilitating efforts to prevent melanoma progression, this up-to-date reference presents the most recent advances in the pathology, molecular biology, and therapy of melanoma in early, high-risk, and advanced stages.
Discusses growth factors, cytokines, receptors, oncogenes, tumor suppressor genes, adhesion molecules, and proteases in melanoma and examines the appropriate use of interferon adjuvant therapy!
Written by leading authorities from the United States and Europe, Molecular Diagnosis and Treatment of Melanoma

details the preclinical and clinical basis for new vaccines based on gangliosides and peptides

explains the roles of chemotherapy and radiosurgery

reviews the molecular features of melanoma and precursor cells

describes the events involved in induction and maintenance of antitumor T-cell response and various escape mechanisms from immune recognition

analyzes melanotic and dysplastic nevi

explores the potential of vaccines that induce antibodies in immunotherapy and vaccines in high-risk melanoma

summarizes cytotoxic chemotherapy in treating metastatic melanoma

elucidates whole-brain radiotherapy, surgical resection, and stereotactic radiosurgery in managing melanoma brain metastasis

and more!
Containing key bibliographic citations for more in-depth study of particular topics, Molecular Diagnosis and Treatment of Melanoma is an excellent resource for oncologists, dermatologists, molecular and cell biologists, immunologists, pathologists, pharmacologists, toxicologists, interns, residents, fellows, and graduate and medical school students in these disciplines.

Su questo libro

Contenuti:

Molecular Features of the Biology of Melanoma

Molecular Features of Melanoma Progression, Ulrich Rodeck and Dorothea Becker
Immunologic Features of Progression in Melanoma, Jürgen C. Becker and Eva-Bettina Bröcker

The Precursor Lesion in Melanoma: Propspects for Prevention

Common Acquired Nevi and Dysplastic Nevi as Precursor Lesions and Risk Markers of Melanoma, John T. Seykora and David E. Elder

Adjuvant Therapy of Resected Cutaneous High-Risk Melanoma

Lymphatic Mapping and Sentinel Lymph Node Biopsy in the Care of the Patient with Melanoma, Douglas S. Reintgen and Andrea Brobeil
Molecular Approaches to Adjuvant Immunological Therapy of Melanoma with Interferon (IFN): The Role of Interferons and Other Cytokines as an Adjunct to Surgery in Intermediate- and High-Risk Melanoma, John M. Kirkwood
The Case for Melanoma Vaccines that Induce Antibodies, Philip O. Livingston
Vaccine Trials in High-Risk Melanoma: Induction of Effector T-Cell Responses to Melanoma, Walter J. Storkus, John M. Kirkwood, and Thomas Tüting
Adjuvant Chemotherapy for Malignant Melanoma, Agop Y. Bedikian and Sewa Singh Legha

Therapy of Advanced Metastatic Melanoma

The Role of Cytotoxic Chemotherapeutic Agents Either Alone or in Combination with Biological Response Modifiers, Michael B. Atkins
Radiosurgery in the Management of Melanoma Brain Metastasis, John C. Flickinger, Salvador Somaza, and Douglas Kondziolka
PCR-Based Detection of Malignant Cells: Toward Molecular Staging?, Ulrich Keilholz and Martina Willhauck

Product Description:

Book by Kirkwood John M

Su questa edizione

• Editore: CRC Press
• Data di pubblicazione: 1998
• ISBN 10: 082470102X
• ISBN 13: 9780824701024
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 330