Eicosanoids, Aspirin, and Asthma - Rilegato

Szczeklik, Andrzej; Gryglewski, Ryszard J.; Vane, John R.

Rilegato

ISBN 10: 0824701461 ISBN 13: 9780824701468

Casa editrice: CRC Press, 1998

Riassunto

Blending basic science with the latest clinical insights, this important book presents new ideas on the molecular biology, biochemistry, crystallography, and pharmacology of eicosanoids, including their interaction with antiinflammatory drugs and their influence on the mechanisms of asthma.
Surveys a rich panorama of clinical symptoms from the European Network on Aspirin-Induced Asthma, the largest database of its kind in the world!
Edited by clinicians with long experience in the field, Eicosanoids, Aspirin, and Asthma

elucidates basic asthma mechanisms such as genetic influences, viruses, ion airway transport, and autoimmunity

profiles the effectiveness of corticosteroids and aspirin desensitization in asthma treatment

devotes special attention to aspirin-induced asthma

reveals new details on the mechanisms of action of anti-inflammatory drugs

provides evidence for the pneumoprotective action of endogenous nitric oxide

highlights recent applications of crystallography in the understanding of the three-dimensional structure of cyclooxygenase

describes new pathways of arachidonic acid metabolism

explores the clinical manifestations in aspirin-induced asthma

and more!
Complete with over 2000 references, Eicosanoids, Aspirin, and Asthma will be welcomed by pulmonologists and pulmonary physicians, pulmonary rehabilitation therapists, respiratory physiologists, immunologists, allergists, pharmacologists, internists, chest physicians, otolaryngologists, pediatricians, molecular and cell biologists, epidemiologists, neuroanatomists, biochemists, and graduate and medical school students in these disciplines.

Su questo libro

Contenuti:

Mechanism of Action of Antiinflammatory Drugs, John R. Vane and Regine M. Botting
Pathways of Arachidonate Metabolism, John C. McGiff and Michael Balazy
Cytochromes P450 and Arachidonic Acid Metabolism, Michael Balazy and John C. McGiff
Mechanisms of Isoprostane Biosynthesis in Humans, Paola Patrignani, Roberto Padovano, Maria Gina Sciulli, Giovanna Santini, Maria Rosaria Panara, Maria Teresa Rotondo, Giulia Renda, and Carlo Patrono
Intracellular Localization of Eicosanoid-Forming Enzymes, Thomas G. Brock and Marc Peters-Golden
Cyclooxygenase-2 Expression in Airway Cells, Peter J. Barnes, Maria G. Belvisi, Robert Newton, and Jane A. Mitchell
Cyclooxygenase Gene Expression and Regulation, Kenneth Kun-yu Wu
NSAID-Induced Apoptosis: A New Therapeutic Activity of Competitive Cyclooxygenase Inhibitors?, Daniel L. Simmons
The Three-Dimensional Structure of Cyclooxygenases, Daniel Picot
The Role of 5-Lipoxygenase Products in a Mouse Model of Allergic Airway Inflammation, Colin D. Funk, Xin-Sheng Chen, Charles G. Irvin, Yuan-Po Tu, and James R. Sheller
Genetic Influences on Asthma, William O. C. M. Cookson
Intrinsic Asthma, Leonardo M. Fabbri, Gaetano Caramori, Bianca Beghè, and Cristina Mapp
Viral Infection and Asthma: The Modulatory Role of Nitric Oxide on Prostaglandin H Synthase, Gert Folkerts and Frans P. Nijkamp
The Pharmacology of Prostaglandin E2: Actions in Human Diseases Involving the Mast Cell, John A. Oates, John J. Murray, David D. Hagaman, James R. Sheller, Ryszard Dworski, and L. Jackson Roberts II, and Howard R. Knapp
Eicosanoids in the Pathogenesis of Exercise- and Allergen-Induced Asthma, Paul M. O'Byrne
Endotoxin-Induced Acute Respiratory Distress Syndrome in Nitric Oxide-Deficient Rats, Pawel P. Wolkow, Ewa Janowska, Joanna B. Bartus, Wojciech Uracz, and Ryszard J. Gryglewski
Eicosanoid Regulation by Glucocorticoids in Asthma, Ryszard Dworski
Mechanisms of Aspirin-Induced Asthma, Andrzej Szczeklik
Leukotrienes in Aspirin-Sensitive Asthma, S. M. Shuaib Nasser and Tak H. Lee
Mast Cell and Eosinophil Responses After Indomethacin in Asthmatics Tolerant and Intolerant to Aspirin, Esther L. Langmack and Sally E. Wenzel
Aspects of Mechanisms in Aspirin-Intolerant Asthma, Barbro Dahlén
Aspirin-Intolerant Asthma: New Insights from Bronchial Mucosal Biopsies, Anthony P. Sampson
Pharmacological Intervention in Generation of Leukotrienes by Eosinophils, Klaus F. Rabe and Gordon Dent
Airway Ion Transport Mechanisms and Aspirin in Asthma, Sebastiano Bianco, Maria Robuschi, Adriano Vaghi, and Piersante Sestini
Role of Autoantibodies Against Endothelial Cells in Severe Asthma, Philippe Lassalle, Michel Joseph, and Andre-Bernard Tonnel
Clinical Course of Aspirin-Induced Asthma: Results of AIANE, Ewa Nizankowska, Mariusz Duplaga, Grazyna Bochenek, and Andrzej Szczeklik
Nasal Polyposis, Niels Mygind, Ronald Dahl, Per L. Larsen, Torben Lildholdt, and Claus Bachert
The Nose in Aspirin-Sensitive Asthma, César Picado and Joaquim Mullol
The Role of Glucocorticoids in the Modulation of Eicosanoid Metabolism in Asthma, Isabelle Vachier, Pascal Chanez, Claude Chavis, Jean Bousquet, and Philippe Godard
Desensitization in Aspirin-Induced Asthma, Donald D. Stevenson

Product Description:

Book by Szczeklik Andrzej Gryglewski Ryszard J Vane John R

Su questa edizione

• Editore: CRC Press
• Data di pubblicazione: 1998
• ISBN 10: 0824701461
• ISBN 13: 9780824701468
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 648