Veterinary Pharmaceuticals in the Environment: 1018 - Rilegato

Rilegato

ISBN 10: 0841269629 ISBN 13: 9780841269620

Casa editrice: OUP USA, 2010

Riassunto

This book discusses and presents data relevant to the significance of veterinary pharmaceuticals in the environment. A broad range of topics is covered, including environmental chemistry studies focusing on transport, mobility, sorption, persistence, and bioavailability of the compounds, as well as development of analytical techniques relevant to detection of the pharmaceuticals in environmental matrices, discussion of ecotoxicological studies of veterinary pharmaceuticals, and information relevant to ecological risk assessments. The primary classes of drugs addressed are veterinary antibiotics and synthetic hormones. The antibiotics include some used in human medicine and others unique to animal medicine. A number of the most widely-used antibiotics are employed in two different ways: therapeutically to cure or prevent diseases, or as growth promoters. Synthetic hormones are utilized to influence the development of animals, in particular in regards to weight gain and body composition. Many of the environmental concerns over veterinary pharmaceuticals arise from runoff and wastes from confined animal feeding operations (CAFOs), where tens of thousands of meat animals are confined in a small area, even over a million in the case of chickens. In such situations, the drugs that are excreted intact or partially metabolized can still be biologically active when they enter the environment; even natural hormones from the animals constitute a significant portion of the overall input of bioactive chemicals.

To date, there have been numerous monitoring studies that have confirmed the existence of very low concentrations of animal pharmaceuticals and hormones, especially in surface waters. The next important question is whether those residues are of any significance in the environment, including questions about how long they persist, where they come from, how they move, whether they accumulate in environmental sinks, and what kinds of biological effects they have. The most prominent controversy may be the one generated around the possibility of antibiotics inducing or sustaining antibiotic-resistant microorganisms in the environment. Another focus is on the hormonal effects on fish and wildlife, especially as the hormones (synthetic or natural) influence reproduction and sexual development in wild mammals, birds, fish, and amphibians.

This book addresses pressing scientific questions in the field of veterinary pharmaceuticals, including the monitoring of the drugs, the development of analytical chemical and immunochemical methods of quantifying low levels of the residues, mobility, biological availability, uptake, and effects on organisms. Several chapters that address risk assessment perspectives are included.

Su questo libro

L'autore:

Keri L. Henderson is a PhD Candidate in the Toxicology program at Iowa State University. Joel R. Coats is Professor of Entomology and Toxicology at Iowa State University

Contenuti:

• Contents
• 1.: PREFACE: Veterinary Pharmaceuticals in the Environment
• Dr. Keri Henderson, Dr. Joel Coats
• 2.: Veterinary pharmaceuticals in the environment: an introduction
• Keri L.D. Henderson, Joel R. Coats
• Fate and bioavailability
• 3.: A Review of the Fate of Manure-Borne, Land-Applied Hormones
• H. Hakk, F.X.M. Casey, Z. Fan, G. L. Larsen
• 4.: Fate of Chlorate Salts Excreted from Animals
• D. J. Smith, C. E. Oliver, H. Hakk, R. C. Anderson, G. L. Larsen
• 5.: Influence of MnO2 on the transformation of oxy- and chlortetracycline in pond water
• Kennedy F. Rubert IV, Curtis J. Hedman, Tan Guo, Joel A. Pedersen
• 6.: Comparative Biotransformation of Fluoroquinolone Antibiotics in Matrices of Agricultural Relevance
• Heinz-Georg Wetzstein, Josef Schneider, Wolfgang Karl
• 7.: Environmental fate and chemistry of a veterinary antibiotic-tylosin
• Dingfei Hu, Keri L.D. Henderson, Joel R. Coats
• 8.: An overview of the fate and effects of antimicrobials used in aquaculture
• Yong-Hak Kim, Carl E. Cerniglia
• 9.: Fate and bioavailability of sulfamethazine in freshwater ecosystems
• Keri L.D. Henderson, Thomas B. Moorman, Joel R. Coats
• Assessing potential environmental impacts
• 10.: Livestock Hormones in Aquatic Ecosystems
• Yue-wern Huang, Dev K. Niyogi, Paul K. Nam, Janet M. Bandeff
• 11.: Characterization of Chlortetracycline-induced Glutathione S-Transferase to Conjugate Chloroacetanilide and Chlorotriazine Herbicides
• Michael H. Farkas, James O. Berry, Diana S. Aga
• 12.: Targets, Effects and Risks in Aquatic Plants Exposed to Veterinary Antibiotics
• Richard A. Brain, Keith R. Solomon, Bryan W. Brooks
• 13.: Risks of agricultural pharmaceuticals in surface water systems and soils
• Keith R. Solomon, Derek G. Hillis, Linda Lissemore, Paul K. Sibley
• 14.: Risk assessment considerations for veterinary medicines in aquatic ecosystems
• Bryan W. Brooks, Richard A. Brain , Duane B. Huggett, Gerald T. Ankley
• Indexes
• Author Index
• Subject Index

Su questa edizione

• Editore: OUP USA
• Data di pubblicazione: 2010
• ISBN 10: 0841269629
• ISBN 13: 9780841269620
• Rilegatura: Copertina rigida
• Numero di pagine: 256
• Redattore: Henderson Keri, Coats Joel