Modeling of Cancer Genesis and Prevention - Rilegato

Voiculetz, Nicolae; Balaban, Alexandru T; Niculescu-Duvaz, Ion; Simon, Zeno

Rilegato

ISBN 10: 0849363799 ISBN 13: 9780849363795

Casa editrice: CRC Press, 1991

Riassunto

This book presents a comprehensive review of the interaction between cancer research and mathematical methods for both investigators in the field and newcomers just entering it. The book's primary focus is on the use of computer-assisted mathematical modeling in carcinogenesis and cancer prevention. The first two chapters include a general presentation of the carcinogenesis and anticarcinogenesis molecular mechanisms, followed by a discussion of mathematical models of triggers for gene regulation. A description of the prediction of both carcinogenicity and mutagenicity using quantum mechanical, topological or physico-chemical indices is presented, as well as a discussion of the QSAR analysis of carcinogenesis-inhibiting compounds (known as blocking or suppressive agents).

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Contenuti

General Mechanisms of Carcinogenesis and Anticarcinogenesis. Trigger Models for Gene Activity Regulation in Carcinogenesis. Quantitative Prediction of Carcinogenic Activity. Topological Correlations and Cancer. QSAR Analysis as Predictive Model for Carcinogens and Mutagens. Quantitative Approach to Carcinogenesis Inhibition: A QSAR Analysis. Index.

Product Description

Book by Voiculetz Nicolae Balaban Alexandru T NiculescuDuv

Dettagli dell'edizione

• Editore: CRC Press
• Data di pubblicazione: 1991
• Lingua: Inglese
• ISBN 10: 0849363799
• ISBN 13: 9780849363795
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 264
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile