Colloidal Carriers for Controlled Drug Delivery and Targeting: Modification, Characterization, and In Vivo Distribution

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9780849377143: Colloidal Carriers for Controlled Drug Delivery and Targeting: Modification, Characterization, and In Vivo Distribution

Colloidal carriers (particles, emulsions) for intravenous administration are a promising approach to achieve controlled release and site-specific delivery of drugs. The success of the systems will depend on their ability to maintain in blood circulation (controlled release system) or to reach target cells (e.g., bone marrow, blood cells). It is well known that the surface properties of i.v. injected particles are important factors determining the organ distribution and fate in vivo. Controlled surface modification could therefore be used to direct the carriers to the desired tissues.

This book deals with the physico-chemical characterization of colloidal drug delivery systems and the influence of these parameters upon in vitro cell uptake and in vivo tissue distribution. Within the book, several different methods and their effect on surface characterization are discussed, and the in vivo tissue distribution of nanoparticles different in size and surface properties (coatings with Poloxamer/Polaximine/ethoxylated nonylphenols) and the carrier properties are examined in detail. The book does not deal with single aspects, but offers a comprehensive treatment of the subject. As a result, the book contributes to a better understanding of the factors influencing the organ distribution of i.v. drug carriers and provides useful information for the rational design of new carriers. It succeeds in clearing the way for future developments and the optimization of carriers for controlled drug delivery.

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Muller
Editore: CRC Press (1991)
ISBN 10: 0849377145 ISBN 13: 9780849377143
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Descrizione libro CRC Press, 1991. Hardcover. Condizione libro: New. 1. Codice libro della libreria DADAX0849377145

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Muller Rainer H.
Editore: Taylor & Francis Group
ISBN 10: 0849377145 ISBN 13: 9780849377143
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Descrizione libro Taylor & Francis Group. Condizione libro: New. pp. 375 This item is printed on demand. Codice libro della libreria 8273006

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Rainer H. Muller
Editore: Taylor Francis Inc, United States (1991)
ISBN 10: 0849377145 ISBN 13: 9780849377143
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Descrizione libro Taylor Francis Inc, United States, 1991. Hardback. Condizione libro: New. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. Colloidal carriers (particles, emulsions) for intravenous administration are a promising approach to achieve controlled release and site-specific delivery of drugs. The success of the systems will depend on their ability to maintain in blood circulation (controlled release system) or to reach target cells (e.g., bone marrow, blood cells). It is well known that the surface properties of i.v. injected particles are important factors determining the organ distribution and fate in vivo. Controlled surface modification could therefore be used to direct the carriers to the desired tissues. This book deals with the physico-chemical characterization of colloidal drug delivery systems and the influence of these parameters upon in vitro cell uptake and in vivo tissue distribution. Within the book, several different methods and their effect on surface characterization are discussed, and the in vivo tissue distribution of nanoparticles different in size and surface properties (coatings with Poloxamer/Polaximine/ethoxylated nonylphenols) and the carrier properties are examined in detail. The book does not deal with single aspects, but offers a comprehensive treatment of the subject. As a result, the book contributes to a better understanding of the factors influencing the organ distribution of i.v. drug carriers and provides useful information for the rational design of new carriers. It succeeds in clearing the way for future developments and the optimization of carriers for controlled drug delivery. Codice libro della libreria BTE9780849377143

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Rainer H. Muller
ISBN 10: 0849377145 ISBN 13: 9780849377143
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Descrizione libro 1991. Hardcover. Condizione libro: New. 1st. Hardcover. Colloidal carriers (particles, emulsions) for intravenous administration are a promising approach to achieve controlled release and site-specific delivery of drugs. The succes.Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. 379 pages. 0.816. Codice libro della libreria 9780849377143

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