Animal Models of Neurological Disease, II: Metabolic Encephalopathies and the Epilepsies: Metabolic Encephalopathies and Epilepsies: 22 - Rilegato

Boulton, Alan A.; Baker, Glen B.

Rilegato

ISBN 10: 0896032116 ISBN 13: 9780896032118

Casa editrice: Humana Pr Inc, 1992

Riassunto

to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric disorders. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general preface to these volumes in order to indicate why we think further - search using animals is necessary and why animal models of psychiatric disorders, in particular, are so important. We recognize that animals should only be used when suitable alternatives are not available. We think it self-e- dent, however, that humans can only be experimented upon in severely proscribed circumstances and alternative pro- dures using cell or tissue culture are inadequate in any models requiring assessments of behavioral change or of complex in vivo processes. However, when the distress, discomfort, or pain to the animals outweighs the anticipated gains for human welfare, then the research is not ethical and should not be carried out. It is imperative that each individual researcher examine his/her own research from a critical moral standpoint - fore engaging in it, taking into consideration the animals’ welfare as well as the anticipated gains. Furthermore, once a decision to proceed with research is made, it is the researcher’s responsibility to ensure that the animals’ w- fare is of prime concern in terms of appropriate housing, feeding, and maximum reduction of any uncomfortable or distressing effects of the experimental conditions, and that these conditions undergo frequent formalized monitoring.

Su questo libro

Recensione:

These books go out of their way to be helpful. Most chapters introduce the animal models against the background of the human (i.e., clinical) context and conclude with a brief summary. Detailed experimental protocols and useful tabulations abound. Descriptions are exhaustive.-Trends in Neurosciences

Contenuti:

Seta et al.: Experimental Models of Human Stroke. Gibson/Huang: Animal Models of Brain Hypoxia. Héroux/Butterworth: Animal Models of the Wernicke-Korsakoff Syndrome. McCandless/FineSmith: Chemically Induced Models of Seizures. Abel/McCandless: The Kindling Model of Epilepsy. Abel/McCandless: Genetically Based Animal Models of Seizures. Blei/Omary/Butterworth: Animal Models of Hepatic Encephalopathies. Murphy/Digout/Crocker: Animal Models for Reye's Syndrome. Kauffman: Animal Models of Niacin-Nicotinamide Deficiency. Dakshinamurti/Sharma/Lal: Pyridoxine Deficiency: Animal Model for CNS Serotonin and GABA Depletion. Qureshi: Animal Models of Hereditary Hyperammonemias. Index.

Su questa edizione

• Editore: Humana Pr Inc
• Data di pubblicazione: 1992
• ISBN 10: 0896032116
• ISBN 13: 9780896032118
• Rilegatura: Copertina rigida
• Numero di pagine: 396
• Redattore: Butterworth Roger F.