Recensione:
The 21 Chapters cover the whole range of techniques, with enough detail about the physical and technical background to satisfy and enable the critical user without swamping him or her; all illustrated with a wide range of cutting-edge applications...The book closes with a valuable series of appendices (acronyms, mass and abundance values, fragmentation patterns etc)...there is no lightweight material or padding in this important and timely book-The European Peptide Society Newsletter
"...useful to newcomers." - SGM Quarterly
Contenuti:
Mass Spectrometry in the Analysis of Peptides and Proteins, Past and Present, Peter Roepstorff. Mass Spectrometry: Ionization Methods and Instrumentation, John R. Chapman. Charged Derivatives for Peptide Sequencing Using a Magnetic Sector Instrument, Joseph Zaia. New Instrumental Approaches to Collision-Induced Dissociation Using a Time-of-Flight Instrument, Bernhard Spengler. Mass Spectrometric Quantification of Neuropeptides, Dominic M. Desiderio. The Identification of Electrophoretically Separated Proteins by Peptide Mass Fingerprinting, John S. Cottrell and Chris W. Sutton. Liquid Chromatography/Mass Spectrometry for the Analysis of Protein Digests, Thomas Covey. Structural Analysis of Protein Variants, Yoshinao Wada. Noncovalent Interactions Observed Using Electrospray Ionization, Brenda L. Schwartz, David C. Gale, and Richard D. Smith. Protein Secondary Structure Investigated by Electrospray Ionization, Carol V. Robinson. The Effect of Detergents on Proteins Analyzed by Electrospray Ionization, Rachele R. Ogorzalek Loo, Natalie Dales, and Philip C. Andrews. Posttranslational Modifications Analyzed by Automated Protein Ladder Sequencing, Rong Wang and Brian T. Chait. Rapid Analysis of Single-Cysteine Variants of Recombinant Proteins, Thomas W. Keough, Yiping Sun, Bobby L. Barnett, Martin P. Lacey, Mark D. Bauer, Ellen S. Wang, and Christopher R. Erwin. Disulfide Bond Location in Proteins, Yiping Sun, Mark D. Bauer, Thomas W. Keough, and Martin P. Lacey. Determination of Loading Values and Distributions for Drugs Conjugated to Proteins and Antibodies by MALDI-MS and ESI-MS, Marshall M. Siegel. Hydrophobic Proteins and Peptides Analyzed by Matrix-Assisted Laser Desorption/Ionization, Kevin L. Schey. Analysis of Glycoproteins and Glycopeptides Using Fast-Atom Bombardment, Geert Jan Rademaker and Jane Thomas-Oates. Identification of Cleaved Oligosaccharides by Matrix-Assisted Laser Desorption/Ionization, David J. Harvey. Structural Characterization of Protein Glycosylation Using HPLC/ Electrospray Ionization Mass Spectrometry and Glycosidase Digestion, Christine A. Settineri and Alma L. Burlingame. Analysis of Complex Protein and Glycoprotein Mixtures by Electrospray Ionization Mass Spectrometry with Maximum Entropy Processing, Brian N. Green, Therese Hutton, and Serge N. Vinogradov. The Use of Databases in Searching the Literature of Biological Mass Spectrometry, Ronald W. A. Oliver and Michael P. Carrier. Appendices. Index.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.