Genomic Clinical Trials and Predictive Medicine - Rilegato

Simon, Richard M.

Rilegato

ISBN 10: 1107008808 ISBN 13: 9781107008809

Casa editrice: Cambridge University Press, 2013

Riassunto

Genomics is majorly impacting therapeutics development in medicine. This book contains up-to-date information on the use of genomics in the design and analysis of therapeutic clinical trials with a focus on novel approaches that provide a reliable basis for identifying which patients are most likely to benefit from each treatment. It is oriented to both clinical investigators and statisticians. For clinical investigators, it includes background information on clinical trial design and statistical analysis. For statisticians and others who want to go deeper, it covers state-of-the-art adaptive designs and the development and validation of probabilistic classifiers. The author describes the development and validation of prognostic and predictive biomarkers and their integration into clinical trials that establish their clinical utility for informing treatment decisions for future patients.

Su questo libro

Recensione:

'This book will be a valuable resource to those involved in genomic clinical trials. The author touches on many of the important issues in this field and provides a useful selection of approaches to handling them.' Matthew Schipper, International Statistical Review

Descrizione del libro:

This book focuses on novel approaches that provide a reliable basis for identifying which patients are likely to benefit from each treatment. Aimed at both clinical investigators and statisticians, it covers the development and validation of prognostic and predictive biomarkers and their integration into clinical trials.

Su questa edizione

• Editore: Cambridge University Press
• Data di pubblicazione: 2013
• ISBN 10: 1107008808
• ISBN 13: 9781107008809
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 153