Lectins - Brossura

Sharon, Nathan

Brossura

ISBN 10: 1402066058 ISBN 13: 9781402066054

Casa editrice: Springer Netherlands, 2010

Riassunto

This Second Edition brings readers up to date with all the latest findings in lectin research. Throughout this new edition, more than 200 figures and some thirty tables help readers visualize and understand key concepts and processes. The book starts with an overview of lectin research followed by a survey of the occurrence of lectins in nature. Other areas covered include the nutritional effects of lectins and their functions in nature.

Su questo libro

Recensione:

"A must for everyone interested in Lectins."
(Robert A. Childs, MRC Glycosciences Laborartory, Imperial College, Harrow, UK in Microbiology Today, 31, November 2004)

"This excellent textbook, prepared by the authors, widely known as the top experts in the field, provides a comprehensive coverage of our present knowledge of structure, functions and applications in Lectins. The volume is very well illustrated by numerous excellent figures. The book is highly recommendable."
(Roald Nexlin, The Weizman Institute of Science, Israel in Immunological Investigations, 33:3, 2004)

Contenuti:

Preface. 1. Introduction. 2. History: The Early Pioneers; Blood Group Specificity; Mitogenic Stimulation; A Tool For Cancer Research; Lectins Galore; From Primary To Three-Dimensional Structures; Tools For Biological And Medical Research; Insight Into Biological Functions; Into Contemporary Lectin Research. 3. Detection, Occurrence And Isolation: Detection; Occurrence; Isolation And Purification. 4. Specificity And Affinity: Methodology; Carbohydrate Specificity; Role Of Oligosaccharide Conformation; Effect Of Multivalency; Energetics Of Protein-Carbohydrate Interactions; Non-Carbohydrate Ligands; Leczymes. 5. Molecular Structure: Plant Lectins; Animal Lectins; Protozoan Lectins; Bacterial Lectins; Viral Hemagglutinins. 6. Combining Sites: Lectin-Carbohydrate Bonds; Plant Lectins; Animal Lectins; Bacterial Lectins; Viral Hemagglutinins. 7. Genetics, Molecular Biology And Evolution: Genetics And Molecular Biology; Evolution Of Carbohydrate Binding Activity. 8. Applications: Methodology; Glycoconjugates In Solution; Cell-Bound Carbohydrates; Mapping Neuronal Pathways; Cell Separation; Mitogenic Stimulation; Anti-Adhesion Therapy; Clinical Uses; Diagnosis And Targeting; Other Applications. 9. Lectin Cytotoxicity And Lectin-Resistant Cells: Mechanism Of Action; Lectin-Resistant Mutants. 10. Nutritional Effects: Lectins In Edible Plants; Deleterious Effects In The Intestinal Tract; Systemic Effects. 11. Functions: Theoretical Considerations; Plant Lectins; Animal Lectins; Microbial Lectins. Abbreviations. Appendix 1: Monosaccharides Recognized By Lectins. Appendix 2: Disaccharides And Oligosacharides. References. Index.

Su questa edizione

• Editore: Springer Netherlands
• Data di pubblicazione: 2010
• ISBN 10: 1402066058
• ISBN 13: 9781402066054
• Rilegatura: Copertina flessibile
• Numero edizione: 2
• Numero di pagine: 476