Systems Analysis of Human Multigene Disorders: 799 - Rilegato

Rilegato

ISBN 10: 1461487773 ISBN 13: 9781461487777

Casa editrice: Springer Nature, 2013

Riassunto

Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance.

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Contenuti

Wellness and Health Omics Linked to the Environment: the WHOLE approach to personalized medicine.- Characterizing Multi-omic Data in Systems Biology.- High-throughput Translational Medicine: Challenges and Solutions.- Computational approaches for human disease gene prediction and ranking.- A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization.- Index.

Dettagli dell?edizione

• Editore: Springer Nature
• Data di pubblicazione: 2013
• ISBN 10: 1461487773
• ISBN 13: 9781461487777
• Rilegatura: Copertina rigida
• Lingua: Inglese
• Numero di pagine: 122
• Redattore: Maltsev Natalia, Rzhetsky Andrey, Gilliam T. Conrad
• Contatto del produttore: {language_tag:it_IT,value:"Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com"}