The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.
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ABRAHAM J. DOMB is Professor for Medicinal Chemistry and Biopolymers at the Faculty of Medicine of the Hebrew University in Jerusalem, Israel. He earned bachelor’s degrees in chemistry, pharmacy and law studies and a Ph.D. in chemistry from Hebrew University. He did his postdoctoral training at MIT and Harvard University and was R&D manager at Nova Pharm in Baltimore between 1988 and 1992. His primary research interests are in biopolymers, controlled drug delivery, cancer therapy, nanoparticulate systems, and forensic sciences.
WAHID KHAN obtained his master’s degree and Ph.D. in pharmaceutics at the National Institute of Pharmaceutical & Educational Research (NIPER) in Mohali, India. He worked with Prof. Abraham J. Domb in The Hebrew University of Jerusalem, Israel, for his post-doctoral research. Currently, he is working as Assistant Professor in the Department of Pharmaceutics at NIPER in Hyderabad, India. His experience includes areas ranging from drug delivery and drug targeting to nanomedicine and biodesign of implantable medical devices.
1. Biodegradable Polymers for Focal Delivery Systems
Wahid Khan, Venu Gopala Swami Challa, Robert Langer, and Abraham J. Domb
2. Implantable Medical Devices
Wahid Khan, Eameema Muntimadugu, Michael Jaffe, and Abraham J. Domb
3. Systemic Targeting Systems-EPR Effect, Ligand Targeting Systems
Prasad V. Pawar, Abraham J. Domb, and Neeraj Kumar
4. Liposomal formulations for Focal and Targeted Drug Delivery in Cancer and Other Diseases
Sean Essex and Vladimir Torchilin
5. Polymer Drug Conjugate in Focal Drug Delivery
Rajan Swami, Dinesh Kumar, Wahid Khan, Ramakrishna Sistla, Nalini Shastri
6. Pharmacokinetic and Pharmacodynamic Aspects of Focal and Targeted Delivery of Drugs
David Stepensky
7. Treatment of Brain Tumors
Betty M. Tyler, Gustavo Pradilla, Uri Hadelsberg, Hansen Bow, and Henry Brem
8. Intranasal Delivery of Neuropeptide-Loaded Nanoparticles and Their Application to Nervous System Therapeutics
Michael J. Kubek, Abraham J. Domb, Daniel J. Kubeka, Michael C. Veronesi
9. Focal Drug Delivery in Inner Ear Therapy
Jing Zou
10. Nanotechnology Based Ophthalmic Drug Delivery System
Fahima Dilnawaz and Sanjeeb Kumar Sahoo
11. Site Specific Ocular Nucleic Acid Delivery
Ravi S. Shukla and Kun Cheng
12. Topical Iontophoresis for Targeted Local Drug Delivery to the Eye and Skin
Taís Gratieri and Yogeshvar N. Kalia
13. Local Drug Delivery to the Oral Cavity
Sheeba Qureshi, Wahid Khan, Michael Perez-Davidi, Ervin I Weiss, Nurit Beyth, and Abraham J. Domb
14. Focal Drug Delivery for Management of Oral Infections
Nurit Beyth, Orith Haramaty and David Polak
15. Segmental-Dependent Drug Absorption and Delivery: The Stomach
Omri Wolk and Arik Dahan
16. Segmental-Dependent Drug Absorption and Delivery: The Intestinal Tract
Omri Wolk and Arik Dahan
17. Nanotechnology Applications in Local Arterial Drug Delivery
Dipti Deshpande, Azizah Jamal-Allial, Kinjal Sankhe, and Mansoor Amiji
18. Drug Eluting Stents
Wahid Khan, Rajesh Thipparaboina, Shady Farah, Judah Z. Weinberger, and Abraham J. Domb
19. Drug-Eluting Vascular Grafts
Jingjia Han and Peter I. Lelkes
20. Delivery Systems for Lymphatic Targeting
Indu Singh, Rajan Swami, Wahid Khan, and Ramakrishna Sistla
21. Spatio-temporal Focal Delivery of Dual Regenerating Factors for Osteochondral Defect Repair
Emil Ruvinov and Smadar Cohen
22. Spatio-temporal Focal Delivery of Dual Regenerating Factors for Osteochondral Defect Repair
Emil Ruvinov and Smadar Cohen
23. Polymer Based Drug Delivery Systems for Solid Tumor Treatment
Ariella Shikanov and Abraham J. Domb
24. Topical Nanointerventions for Therapeutic and Cosmeceutical Applications
Vandana B. Patravale and Preshita P. Desai
25. Focal Drug Delivery to the Nail
Sudaxshina Murdan
26. Drug Delivery to Wounds, Burns and Diabetes Related UlcersSonam Jain, Abraham J. Domb, and Neeraj Kumar
27. Vaginal Drug Delivery
Emily A. Krogstad, Michael J. Rathbone, and Kim A. Woodrow
28. Prolonged Duration Local Anesthesia
J. Brian McAlvin and Daniel S. Kohane
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ. 720 pp. Englisch. Codice articolo 9781461494331
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Condizione: NEW. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes fundamental introductory chapters for focal drug deliveryDescribes drug delivery to body sites/systemProvides an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences. Codice articolo 4199995
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