Translational Research in Traumatic Brain Injury - Rilegato

Rilegato

ISBN 10: 1466584912 ISBN 13: 9781466584914

Casa editrice: CRC Press, 2015

Riassunto

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow.

Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas:

• Epidemiology
• Pathophysiology
• Diagnosis
• Current treatment strategies and sequelae
• Future therapies

Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Su questo libro

L'autore:

Edited by

Daniel Laskowitz, MD, MHS, professor of neurology, anesthesiology & neurobiology; and director, Neurovascular Laboratories, Duke University Medical Center, Durham, North Carolina, USA

Gerald A. Grant, MD, FACS, division chief, Pediatric Neurosurgery; vice chair for pediatric neurosurgery and associate program director; and associate professor, Department of Neurosurgery; Stanford University/Lucile Packard Children's Hospital, California, USA

Contenuti:

Epidemiology

Epidemiology

Sports Injury

Pathophysiology

Diffuse Axonal Injury

BBB Breakdown

Cellular

Neuroplasticity after TBI

Neuroinflammation

Neurosteroids

Genetics of TBI

Acute Neuronal Excitability and Seizures after TBI

Animal Models

Diagnosis of TBI

Biomarkers

Radiology

Current Treatment and Sequelae

Current Therapeutic Strategies

Epilepsy after TBI

Neurocognitive Sequelae and Relationship to PTSD

Management and Monitoring of Cerebral Physiology and ICP

Clinical Trials and Future Therapies

Clinical Trials in TBI

Clinical Trials in PTSD

Cell-based Therapies in TBI

Neurostimulation

Machine/Brain Interface

Su questa edizione

• Editore: CRC Press
• Data di pubblicazione: 2015
• ISBN 10: 1466584912
• ISBN 13: 9781466584914
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 412
• Redattore: Laskowitz Daniel, Grant Gerald