Some mild stresses have positive effects on survival and aging as shown in animal models. There is also a large body of research that demonstrates these hormetic effects on aging, health, and resistance to severe stresses and diseases in human beings. However, the data are dispersed in the literature and are not always interpreted as hormetic effects. Hormesis in Health and Disease reviews the evidence for hormesis in humans as achieved through a variety of stresses or stimuli, and discusses mechanisms of hormesis and its ethical and legal issues.
Divided into four sections, this book presents the current state of research, including questions, debates, doubts, and controversies in hormesis. Section I covers the history and terminology of hormesis, describing its main features and providing necessary background information. Section II shows that hormetic effects can be caused by various stresses―including physical exercise, nutritional components, fasting, micronutrients, irradiation, heat, ischemia, and mental challenge―and can be observed both in organs and at the organism level. Section III reviews possible mechanisms of hormesis that have been elucidated at this point. Section IV discusses the wider consequences hormesis may have for everyone.
This book demonstrates that health beneficial hormetic effects do exist in human beings. It offers information to inspire key players to initiate new strategies to elucidate the strengths and limits of the dual nature of stress.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Suresh I.S. Rattan, PhD, DSc, is an internationally renowned biogerontologist at the Laboratory of Cellular Ageing, Department of Molecular Biology and Genetics, Aarhus University, Denmark. He is one of the pioneers for the testing and application of hormesis in aging research and interventions. His research expertise includes elucidating the molecular mechanisms of human cellular aging. Dr. Rattan is the discoverer of the aging-modulatory effects of kinetin and zeatin, which are now used in several skin care products. He is the editor-in-chief of the journal Biogerontology. He has published numerous original research papers and reviews, and is the author of popular science books for children in several languages.
Éric Le Bourg, PhD, DSc, is an internationally renowned biogerontologist at the French National Center for Scientific Research (CNRS), Université Paul Sabatier, Toulouse, France. He is well known for his studies on the effects of mild stress in Drosophila but is also working on learning, behavior, and demography matters. He has published numerous papers and has written several books on aging in French for the lay public and academics on the biology, demographic, and social matters.
Both editors have previously collaborated and edited the book Mild Stress and Healthy Aging (Springer 2008) and brought out two special issues of the international peer-reviewed journals Biogerontology (2006) and Dose Response (2010).
Section I History and Terminology
Brief History of Hormesis and Its Terminology
Edward J. Calabrese
Pre- and Postconditioning Hormesis
F.A.C. Wiegant
Section II Evidence for Hormesis in Human Beings
Exercise and Hormesis: Shaping the Dose–Response Curve
Zsolt Radak
Nutritional Components: How They Enhance the Ability to Adapt
Antje R. Weseler and Aalt Bast
Periodic Fasting and Hormesis
Yan Y. Lam and Eric Ravussin
Iron, Metabolic Syndrome, and Hormesis
Kupper A. Wintergerst and Lu Cai
Radiation Exposure
Alexander Vaiserman
Thermal Hydrotherapy as Adaptive Stress Response: Hormetic Significance, Mechanisms, and Therapeutic Implications
G. Scapagnini, S. Davinelli, N.A. Fortunati, D. Zella, and M. Vitale
Cardiac Ischemic Preconditioning and the Ischemia/Reperfusion Injury
Andreas Simm and Rüdiger Horstkorte
Cerebral Ischemia
Yannick Béjot and Philippe Garnier
Optimal Stress, Psychological Resilience, and the Sandpile Model
Martha Stark
Section III Molecular Mechanisms of Hormesis
Molecular Stress Response Pathways as the Basis of Hormesis
Dino Demirovic, Irene Martinez de Toda, and Suresh I.S. Rattan
Inflammatory Pathways
Salvatore Chirumbolo
Oxidative Stress Response Pathways: Role of Redox Signaling in Hormesis
Li Li Ji
Section IV Hormesis in Risk Assessment
Relating Hormesis to Ethics and Policy: Conceptual Issues and Scientific Uncertainty
George R. Hoffmann
Hormesis and Risk Assessment
Edward J. Calabrese
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
Spese di spedizione:
EUR 18,47
Da: Regno Unito a: U.S.A.
Da: Chiron Media, Wallingford, Regno Unito
Hardcover. Condizione: New. Codice articolo 6666-TNFPD-9781482205459
Quantità: 5 disponibili
Da: Biblios, Frankfurt am main, HESSE, Germania
Condizione: New. Codice articolo 1897779493
Quantità: 4 disponibili
Da: Lucky's Textbooks, Dallas, TX, U.S.A.
Condizione: New. Codice articolo ABLIING23Mar2716030137311
Quantità: Più di 20 disponibili
Da: moluna, Greven, Germania
Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Suresh I.S. Rattan, PhD, DSc, is an internationally renowned biogerontologist at the Laboratory of Cellular Ageing, Department of Molecular Biology and Genetics, Aarhus University, Denmark. He is one of the pioneers for the testing and a. Codice articolo 596053645
Quantità: Più di 20 disponibili
Da: Ria Christie Collections, Uxbridge, Regno Unito
Condizione: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Codice articolo ria9781482205459_lsuk
Quantità: Più di 20 disponibili
Da: PBShop.store US, Wood Dale, IL, U.S.A.
HRD. Condizione: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Codice articolo L1-9781482205459
Quantità: Più di 20 disponibili
Da: PBShop.store UK, Fairford, GLOS, Regno Unito
HRD. Condizione: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Codice articolo L1-9781482205459
Quantità: Più di 20 disponibili
Da: Revaluation Books, Exeter, Regno Unito
Hardcover. Condizione: Brand New. 1st edition. 364 pages. 9.25x6.25x1.00 inches. In Stock. This item is printed on demand. Codice articolo __1482205459
Quantità: 1 disponibili
Da: Revaluation Books, Exeter, Regno Unito
Hardcover. Condizione: Brand New. 1st edition. 364 pages. 9.25x6.25x1.00 inches. In Stock. Codice articolo x-1482205459
Quantità: 2 disponibili
Da: AHA-BUCH GmbH, Einbeck, Germania
Buch. Condizione: Neu. Neuware - There is now a large amount of data available for human beings, showing health beneficial hormetic effects of mild stresses from physical, chemical, nutritional, and mental sources. However, these data are dispersed in the literature and not always interpreted as hormetic effects, thus restricting their full apprehension and application. A comprehensive discussion of the research, this book is composed of four sections: (I) History and Terminology, (II) Evidence for Hormesis in Human Beings, (III) Molecular Mechanisms of Hormesis, and (IV) Hormesis in Risk Assessment. Codice articolo 9781482205459
Quantità: 2 disponibili