Articoli correlati a Epithelial Polarity
Epithelial cells exhibit an apical–basolateral axis of polarity that is generated during embryogenesis, is maintained throughout adult life in the face of constant cell regeneration, and is perturbed in several epithelial-associated diseases. We examine the structural and functional organization of epithelial tissues, as well as the events critical for generating epithelial asymmetry including vectorial trafficking of proteins and lipids, association of signaling and polarity proteins with subdomains of the plasma membrane, and 3D orientation of epithelial cells in response to cell–cell and cell–matrix interactions. As a paradigm to understand how these three processes are coordinated in time and space, we explore apical lumen formation. We also examine the final steps in epithelial morphogenesis, including brush border morphogenesis and ciliogenesis. Finally, we provide examples of disease processes that result from defects in epithelial polarity including diabetes insipidus, microvillar inclusion disease, hereditary deafness, ciliopathies, and cancer.
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Book by Apodaca Gerard Gallo Luciana I
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- EditoreMorgan & Claypool
- Data di pubblicazione2013
- ISBN 10 1615043985
- ISBN 13 9781615043989
- RilegaturaCopertina flessibile
- Numero di pagine113
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Epithelial Polarity (Colloquium Building Blocks of the Cell: Cell Structure and Function)
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Morgan & Claypool Life Sciences
(2013)
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ISBN 13: 9781615043989
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Epithelial Polarity (Colloquium Building Blocks of the Cell: Cell Structure and Function)
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(2013)
ISBN 10: 1615043985
ISBN 13: 9781615043989
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Descrizione libro Softcover. Condizione: new. Epithelial cells exhibit an apicalbasolateral axis of polarity that is generated during embryogenesis is maintained throughout adult life in the face of constant cell regeneration and is perturbed in several epithelialassociated diseases We examine the structural and functional organization of epithelial tissues as well as the events critical for generating epithelial asymmetry including vectorial trafficking of proteins and lipids association of signaling and polarity proteins with subdomains of the plasma membrane and 3D orientation of epithelial cells in response to cellcell and cellmatrix interactions As a paradigm to understand how these three processes are coordinated in time and space we explore apical lumen formation We also examine the final steps in epithelial morphogenesis including brush border morphogenesis and ciliogenesis Finally we provide examples of disease processes that result from defects in epithelial polarity including diabetes insipidus microvillar inclusion disease hereditary deafness ciliopathies and cancer Table of Contents Introduction Epithelial Cell Organization and Asymmetry Generation and Maintenance of Epithelial Polarity Diseases that Result from Defects in Epithelial Polarity Acknowledgments References Author Biographies. Codice articolo DADAX1615043985
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Epithelial Polarity (Colloquium Series on Building Blocks of the Cell: Cell Struc) by Apodaca, Gerard, Gallo, Luciana I. [Paperback ]
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Epithelial Polarity
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Epithelial Polarity
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Epithelial Polarity
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Descrizione libro Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Epithelial cells exhibit an apical-basolateral axis of polarity that is generated during embryogenesis, is maintained throughout adult life in the face of constant cell regeneration, and is perturbed in several epithelial-associated diseases. We examine the structural and functional organization of epithelial tissues, as well as the events critical for generating epithelial asymmetry including vectorial trafficking of proteins and lipids, association of signaling and polarity proteins with subdomains of the plasma membrane, and 3D orientation of epithelial cells in response to cell-cell and cell-matrix interactions. As a paradigm to understand how these three processes are coordinated in time and space, we explore apical lumen formation. We also examine the final steps in epithelial morphogenesis, including brush border morphogenesis and ciliogenesis. Finally, we provide examples of disease processes that result from defects in epithelial polarity including diabetes insipidus, microvillar inclusion disease, hereditary deafness, ciliopathies, and cancer. Codice articolo 9781615043989
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