Reports of influenza-like illnesses date back to the Middle Ages, and outbreaks of influenza likely afflicted humans long before that. Over the last half century, influenza virus research has led to the development of two classes of antivirals – ion channel and neuraminidase inhibitors. Recently, a method of the artificial generation of an influenza virus was established. This system has been instrumental in the development of novel influenza vaccines and in the understanding of viral pathogenicity and the functions of viral proteins. Influenza Virus: Methods and Protocols summarizes the current techniques that have made this progress possible, ranging from protocols for virus isolation, growth, and subtyping to procedures for the efficient generation of any influenza virus. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and easily accessible, Influenza Virus: Methods and Protocols seeks to serve both professionals and novices with the techniques used in numerous laboratories around the world that are, thus, the building blocks that underpin almost all influenza virus research.
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From the reviews:
“The chapters are all extremely informative both for a new researcher in the field or for the more seasoned flu researcher, and I think this book would be a valuable addition to the laboratory bookshelf. ... This really is a multi-disciplinary book, which I personally think is very beneficial, as influenza researchers need to be able to approach research from all angles to try to stay one step ahead of an ever evolving virus.” (Ruth Harvey, Microbiology Today, November, 2012)
“This book describes methods to diagnose and culture influenza viruses as well as procedures used to evaluate antiviral drugs and to evaluate and produce vaccines to new viral strains. It provides detailed, step-by-step procedures for all aspects of influenza research. ... Researchers in the field of virology are the intended audience. The techniques described in the book have been used in numerous laboratories around the world and will be useful for students as well as established scientists.” (Rebecca T. Horvat, Doody’s Book Reviews, July, 2012)
1. Influenza Viruses – An Introduction
Yoshihiro Kawaoka and Gabriele Neumann
2. Influenza Virus Isolation
Scott Krauss, David Walker, and Robert G. Webster
3. Influenza Virus Titration, Antigenic Characterization, and Serological Methods for Antibody Detection
Alexander Klimov, Amanda Balish, Vic Veguilla, Hong Sun, Jarad Schiffer, Xiuhua Lu, Jacqueline M. Katz, and Kathy Hancock
4. Diagnosis of Influenza Virus
Kirsten St. George
5. Solid-phase Assays of Receptor-binding Specificity
Mikhail N. Matrosovich and Alexandra S. Gambaryan
6. The Chemiluminescent Neuraminidase Inhibition Assay: A Functional Method for Detection of Influenza Virus Resistance to the Neuraminidase Inhibitors
Margaret Okomo-Adhiambo, Aeron C. Hurt, and Larisa V. Gubareva
7. The Fluorescence Neuraminidase Inhibition Assay: A Functional Method for Detection of Influenza Virus Resistance to the Neuraminidase Inhibitors
Aeron C. Hurt, Margaret Okomo-Adhiambo, and Larisa V. Gubareva
8. Animal Models
Edwin J.B. Veldhuis Kroeze, Thijs Kuiken, and Albert D.M.E. Osterhaus
9. Influenza Virus Surveillance, Vaccine Strain Selection and Manufacture
Klaus Stöhr, Doris Bucher, Tony Colgate, and John Wood
10. Genetic Engineering of Live Attenuated Influenza Viruses
Hong Jin, Zhongying Chen, Jonathan Liu, and George Kemble
11. Influenza A Virus Molecular Virology Techniques
Bin Zhou and David E. Wentworth
12. Reverse Genetics of Influenza Viruses
Gabriele Neumann, Makoto Ozawa, and Yoshihiro Kawaoka
13. Genetic Analysis
Gavin J.D. Smith, Justin Bahl, and Vijaykrishna Dhanasekaran
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Descrizione libro Condizione: New. Codice articolo 16649644-n
Descrizione libro Condizione: New. Codice articolo 16649644-n
Descrizione libro Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes cutting-edge methods and protocolsProvides step-by-step detail essential for reproducible resultsContains key notes and implementation advice from the expertsReports of influenza-like illnesses date back to the Middle Ag. Codice articolo 4259175
Descrizione libro Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Reports of influenza-like illnesses date back to the Middle Ages, and outbreaks of influenza likely afflicted humans long before that. Over the last half century, influenza virus research has led to the development of two classes of antivirals - ion channel and neuraminidase inhibitors. Recently, a method of the artificial generation of an influenza virus was established. This system has been instrumental in the development of novel influenza vaccines and in the understanding of viral pathogenicity and the functions of viral proteins. Influenza Virus: Methods and Protocols summarizes the current techniques that have made this progress possible, ranging from protocols for virus isolation, growth, and subtyping to procedures for the efficient generation of any influenza virus. Written in the successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Influenza Virus: Methods and Protocols seeks to serve both professionals and novices with the techniques used in numerous laboratories around the world that are, thus, the building blocks that underpin almost all influenza virus research. 248 pp. Englisch. Codice articolo 9781617796203
Descrizione libro Buch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Reports of influenza-like illnesses date back to the Middle Ages, and outbreaks of influenza likely afflicted humans long before that. Over the last half century, influenza virus research has led to the development of two classes of antivirals - ion channel and neuraminidase inhibitors. Recently, a method of the artificial generation of an influenza virus was established. This system has been instrumental in the development of novel influenza vaccines and in the understanding of viral pathogenicity and the functions of viral proteins. Influenza Virus: Methods and Protocols summarizes the current techniques that have made this progress possible, ranging from protocols for virus isolation, growth, and subtyping to procedures for the efficient generation of any influenza virus. Written in the successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Influenza Virus: Methods and Protocols seeks to serve both professionals and novices with the techniques used in numerous laboratories around the world that are, thus, the building blocks that underpin almost all influenza virus research. Codice articolo 9781617796203
Descrizione libro Hardcover. Condizione: new. Codice articolo 9781617796203
Descrizione libro Hardcover. Condizione: Brand New. 2012 edition. 244 pages. 10.10x7.10x1.10 inches. In Stock. Codice articolo x-1617796204
Descrizione libro Condizione: New. This book reviews current knowledge of viral pathogenicity, the functions of viral proteins and the development of novel influenza vaccines, ranging from protocols for virus isolation, growth, and subtyping to procedures for the generation of influenza virus. Editor(s): Kawaoka, Yoshihiro; Neumann, Gabriele. Series: Methods in Molecular Biology. Num Pages: 234 pages, 19 black & white tables, biography. BIC Classification: MJCJ; MMFM. Category: (P) Professional & Vocational. Dimension: 187 x 316 x 21. Weight in Grams: 670. . 2012. 2012th Edition. Hardcover. . . . . Codice articolo V9781617796203