Major advances in ultrasound, prenatal diagnosis and therapy, and fetal assessment are furthering fetal medicine and clinical perinatology. These developments include: progress in 3-dimensional and color Doppler ultrasound for insights into early embryonic structure and function, counseling for pre-embryonic research, genetic counseling and prenatal informed consent, the use of cardiotocograms (CTGs), ultrasound imaging, Doppler ultrasound, analysis of nucleated red blood cells, and a broad range of clinical topics ranging from the Internet to neonatal intensive care. Under the editorship of Dr. Frank Chervenak and Professors Asim Kurjak and Zoltan Papp, authors and editors of many respected books in this field, The Fetus as a Patient: The Evolving Challenge provides detailed, authoritative coverage of the latest developments in fetal medicine and clinical perinatology. Following an introductory chapter on the moral foundations of leadership in fetal medicine, the book presents 38 chapters in four sections dealing with new developments in ultrasound, the state of the art of prenatal diagnosis and therapy, the challenge of fetal assessment and current perspectives on clinical perinatology. The volume is extensively illustrated throughout and includes bibliographic references and index. The Fetus as a Patient elucidates the current work of the Board of Directors and invited speakers of the International Society of the Fetus as a Patient, which is dedicated to improving all dimensions of fetal diagnosis and therapy.
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INTRODUCTION
The moral foundations of leadership in fetal medicine, F. Chervenak, L. McCullough, A. Kurjak, Z. Papp
NEW DEVELOPMENTS IN ULTRASOUND
The assessment of morphological and vascular development of the early embryo,
A. Kurjak, T. Hafner, I. Bekavac
Threatened abortion: new insights by color Doppler, three- and 4-dimensional ultrasound, S. Kupesic, A. Kurjak, A. Aksamija
Venous return in monochorionic twin pregnancy in the late first trimester, A. Matias and N. Montenegro
First-trimester diagnosis of fetal abnormalities by two and three-dimensional sonoembryology, H. Takeuchi
Chiari II malformation in the fetus, V. D'Addario, V. Pinto, L. Di Cagno
Transvaginal three-dimensional volume assessment of the fetal brain structure, R. Pooh, K. Pooh
Human fetal pulmonary arterial blood flow, JJ.A.M. Laudy, J.W. Wladimiroff
Sonographic examination of the uterine cervix, T. Chaiworapongsa, J. Espinoza, K. Kalache, M.-T. Gervasi, R. Romero
THE STATE OF THE ART OF PRENATAL DIAGNOSIS AND THERAPY
Medical and ethical aspects of pre-embryo research, J.G. Schenker
The change in public demand for genetic counseling in the last 25 years, Z. Papp
Prenatal informed consent for sonogram: the time for first-trimester nuchal translucency has come, S.T. Chasen, D.W. Skupski, L.B. McCullough, F.A. Chervenak
Prenatal diagnosis of fetal cells in maternal blood by comparative genomic hybridization, Y.H. Yang, S.H. Kim, J.E. Jung
Prenatal diagnosis of hemoglobinopathies, A.J. Antsaklis
Prenatal diagnosis of b-thalassemia: Sardinian experience of 6000 cases, G. Monni, M.A. Zoppi, R.M. Ibba
Amniocentesis, T. Stefos
Selective reduction, M.I. Evans, R.J. Wapner
THE CHALLENGE OF FETAL ASSESSMENT
Evaluation of intrapartum long-term cardiotocography with artificial neural network analysis, K. Maeda, M. Utsu, Y. Noguchi, F. Matsumoto
Objective definition of intrauterine growth restriction and practical consequences, G. Mandruzzato, Y.J. Meir, G. Maso, L. Fischer
Fetal risks of macrosomia, V. Váradi
Normal and abnormal growth in multiple pregnancies, I. Blickstein
Twin-twin transfusion syndrome, R.A. Quintero
Non-immune fetal hydrops, H.N. Winn
Advances in the diagnosis of intrapartum asphyxia, R. Luzietti, G. Clerici, K.G. Rosen, G.C. di Renzo
The role of nucleated red blood cells in obstetrics, M.Y. Divon, A. Ferber
CURRENT PERSPECTIVES ON CLINICAL PERINATOLOGY
Perinatal medicine in the information age, I.E. Zador, S.C. Blackwell, R.J. Sokol, M.I. Evans
Low-molecular-weight heparin in perinatal medicine, D. Blickstein, I. Bickstein
Breast cancer and pregnancy, E. Mathieu, P. Merviel, E. Barranger, J.M. Antoine, S. Uzan
Substance abuse during pregnancy, L.S. Voto, A.J. Siufi
The dilemma of toxoplasmosis, M. Mahran
Should we be using repeated doses of antenatal corticosteroids? J.P. Newnham, T.J.M. Moss, I. Nitsos, D. Sloboda, J. Challis
Fetal macrosomia: prediction, timing, and mode of delivery, C. Yabes-Almirante
Clinical dimensions of pre-eclampsia, E.V. Cosmi, F. Pierucci, G.M. Terracina, R. La Torre, L. Maranghi, E. Cosmi, M.M. Anceschi
Pathophysiology of pre-eclampsia, P. Merviel, L. Carbillon, J.-C. Challier, M. Beaufils, S. Uzan
New therapeutic developments in brain-orientated intensive care in the term and preterm newborn, L. Cornette, M. Levene
Index
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