Current Topics in Microbiology and Immunology / Ergebnisse Der Microbiologie Und Immunitatsforschung: 67 - Rilegato

Arber, W.; Haas, R.; Henle, W.; Hofschneider, P. H.; Humphrey, J. H.; Jerne, N. K.; Koldovsky, P.; Koprowski, H.; Maaloe, O.; Rott, R.; Schweiger, H. G.; Sela, Michael; Vogt, P. K.; Wecker, E.

Rilegato

ISBN 10: 3540068384 ISBN 13: 9783540068389

Casa editrice: Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 1974

Riassunto

Prominent progress in molecular biology was only made when it became possible to separate functionally distinct molecules by taking advantage of their biophysical properties. Likewise, the analysis of the functions of hetero- geneous populations of immunocompetent cells, as to the functional properties of their various subpopulations, can not be done until these can be isolated in reasonably pure form by selective fractionation. During the last few years significant advances have been made in this field, and cells have been separated according to size, density or charge (MILLER et aI. , 1969; SHORTMAN, 1968; ANDERSSON, 1973 c), or by taking advantage of more specific surface markers to allow selective depletion or enrichment of a given subpopulation of cells (WIGZELL and ANDERSSON, 1971). Although separation techniques have been used in a variety of cellular systems, they have been particularly useful in the study of reticuloendothelial cells and primarily in the study of cells partici- pating in the immune responses. Quite extensive reviews have been written which well cover the methods used for separation of cells and the results obtained with the various approaches (WIGZELL and ANDERSSON, 1971; SHORTMAN, 1972). To review this work is becoming a more and more voluminous task. As data rapidly accumulate, we will not try to make such a complete review.

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Contenuti:

Specific Fractionation of Immunocompetent Cells. Applications in the Analysis of Effector Cells Involved in Cell Mediated Lysis..- Decoding of Regulator Signals at the Microbial Surface.- Predicting what Antibodies an Antigen will Induce: The Inadequacy of the Determinant Model.- Cell-Mediated Immunity in Certain Parasitic Infections.- Author Index.

Su questa edizione

• Editore: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
• Data di pubblicazione: 1974
• ISBN 10: 3540068384
• ISBN 13: 9783540068389
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 166