The Neuregulin-I/ErbB Signaling System in Development and Disease (Advances in Anatomy, Embryology and Cell Biology): Advances in Anatomy, Embryology and Cell Biology, Volume 190 - Brossura

Britsch, Stefan

Brossura

ISBN 10: 3540371052 ISBN 13: 9783540371052

Casa editrice: Springer, 2007

Riassunto

Neuregulins are EGF-like growth and differentiation factors that interact with tyrosine kinase receptors of the ErbB family. Neuregulin signals are also involved in the development diseases including breast cancer, heart disease and the pathogenesis of schizophrenia. This book reviews the biology of Neuregulins and their receptors and summarizes recent research, which has established crucial functions of this signaling system during development and disease.

Su questo libro

Dalla quarta di copertina:

Neuregulins are EGF-like growth and differentiation factors that interact with tyrosine kinase receptors of the ErbB family. this signailing system has a wide range of functions during development of the nervous system, the heart, and the mammary gland. Furthermore, Neuregulin signals are also involved in the development of human diseases including breast cancer, heart disease and the pathogenesis of schizophrenia.

This monograph reviews the biology of Neuregulins and their receptors and summarizes recent research, which has established crucial functions of this signaling system during development and disease. 

Contenuti:

Introduction – Molecular control of development.- Biology of the Neuregulin/ErbB signaling network.- Neuregulins and their receptors.- Developmental functions of the Neuregulin-1/ErbB signalling pathway.- Interacting molecules – the Sox10/ErbB connection.- NRG-1/ErbB signals and disease.- Abbreviations.- References.- Subject index

Su questa edizione

• Editore: Springer
• Data di pubblicazione: 2007
• ISBN 10: 3540371052
• ISBN 13: 9783540371052
• Rilegatura: Copertina flessibile
• Numero edizione: 1
• Numero di pagine: 84