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Nitric Oxide (NO) is a free radical, a gas, and a pluripotent product of Mammalian cells. Only a few years ago, scientific discussions of NO were largely held in the context of the chemistry of air pollution. Now, however, the great significance of NO as a signalling and cytotoxic molecule has captured the attention of the biomedical community.
This book provides a very up-to-date review of the role of NO in sepsis and ARDS. Consideration is given to NO both as a pathophysiologic mediator as well as a therapeutic agent. An internationally recognized group of scientists and clinicians have contributed chapters dealing with cutting-edge science and practical clinical strategies. Numerous tables and charts have been included to aid the reader in understanding this fascinating and important subject.
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Biochemistry of Nitric Oxide and Regulation of Gene Expression.- Biosynthesis of Nitric Oxide: An Overview.- Biochemistry and Synthesis of NO in Sepsis.- Effect of Hypoxia on Inducible Nitric Oxide Synthase (iNOS) in Renal Mesangial Cells.- Vascular Smooth Muscle Function under Conditions of Sepsis and Endotoxemia.- Nitric Oxide as a Mediator in Gram-Positive Sepsis.- Effects of Nitric Oxide on various Cell Types and Organs.- Nitric Oxide and the Heart in Sepsis.- Influence of Nitric Oxide on Cardiac Systolic and Diastolic Function.- Cellular Actions of Nitric Oxide on the Circulatory System.- Role of Nitric Oxide in Cerebral Ischemia.- Platelet Regulation and Damage in Vascular Thrombotic and Septic Disorders.- Nitric Oxide as a Mediator of Hypotension and Inflammation in Sepsis.- Effect of Nitric Oxide on Intestinal Epithelial Structure and Function.- Nitric Oxide in Shock.- Inhibition of Nitric Oxide Synthase Activity in Circulatory Shock: Friend or Foe?.- Use of Nitric Oxide Synthase Inhibitors to reverse Hyperdynamic Circulation and MOF.- Cardiovascular Alterations associated with Interleukin-2 Therapy.- Blocking the Effects of Nitric Oxide in Septic Shock.- Inhibition of Nitric Oxide Production in Clinical Septic Shock.- Nitric Oxide and the Lung.- Role of Nitric Oxide in Pulmonary Vascular Dysfunction.- Endogenous Nitric Oxide Formation in the Respiratory System.- Pulmonary Vascular Regulation by Endogenous Nitric Oxide.- Nitric Oxide Inhalation in RDS and ARDS.- Inhaled Nitric Oxide: A Review.- Monitoring and Safety of Inhaled Nitric Oxide.- Persistent Pulmonary Hypertension of the Newborn.- Almitrine and Inhaled Nitric Oxide in Acute Respiratory Failure.- Nitric Oxide Inhalation in ARDS.- Inhaled Nitric Oxide: The Light and Shadow of a Therapeutic Breakthrough.
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Descrizione libro Springer Verlag, New York, 1995. Hardcover. Condizione: Very Good Ex-Library Cond Book. 430 pgs. Sections cover: biochemistry of nitric oxide and regulation of gene expression; effects of nitric oxide on various cell types and organs; nitric oxide in shock; nitric oxide and the lung; nitric oxide inhalation in RDS and ARDS; subject index. Provides a review of the role of NO in sepsis and ARDS. Consideration is given to NO both as a pathophysiological mediator as well as a therapeutic agent. Light blue boards show slight wear to corners. Size: 8vo - over 7¾" - 9¾" tall. Book. Codice articolo B025651
Descrizione libro Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 1995. Condizione: Good. Volume 24. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. No dust jacket. Codice articolo 4666332
Descrizione libro Springer Verlag, Secaucus, New Jersey, U.S.A., 1995. Hard Cover. Condizione: Near Fine. Condizione sovraccoperta: No DJ. first Edition, First Printing. This is a near fine, unmarked, hardcover first edition, first printing copy in a blue cloth binding, no DJ. Codice articolo 055588