Articoli correlati a An Introduction to the Hematopoietic Stem Cell Niche
Hematopoiesis is maintained throughout the lifetime of an organism by a specialized group of rare cells known as the hematopoietic stem cells (HSCs). These cells are defined by their ability to self-renew to give rise to similar daughter HSCs, and to differentiate into all the lineages of blood cells. The region where HSCs reside to fulfil these tasks is known as the stem cell niche. In a niche, neighboring subsets of cells and extracellular substrates house stem cells and provide specialized signals to modulate stem cell self renewal and progeny production. Many studies have identified key components of the niche required to maintain the HSCs in their primitive state. However, the exact location of the HSC niche is yet to be clearly identified. Understanding all of the interactions between the stem cells and their microenvironment may yield practical methods for manipulating stem cells to achieve therapeutic outcomes in various disease settings.
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L'autore:
Narges Rashidi, Ph.D., is currently a post-doctoral researcher at Imperial College London. Her research involves studying the hematopoietic stem cell niche as a potential therapeutic target for leukemia and infection. Dr. Rashidi received her Ph.D. degree at University of Southern California and her bachelor’s degree in University of Tehran, Iran.
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- EditoreScholars' Press
- Data di pubblicazione2013
- ISBN 10 3639700422
- ISBN 13 9783639700428
- RilegaturaCopertina flessibile
- Numero di pagine80
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Descrizione libro Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Hematopoiesis is maintained throughout the lifetime of an organism by a specialized group of rare cells known as the hematopoietic stem cells (HSCs). These cells are defined by their ability to self-renew to give rise to similar daughter HSCs, and to differentiate into all the lineages of blood cells. The region where HSCs reside to fulfil these tasks is known as the stem cell niche. In a niche, neighboring subsets of cells and extracellular substrates house stem cells and provide specialized signals to modulate stem cell self renewal and progeny production. Many studies have identified key components of the niche required to maintain the HSCs in their primitive state. However, the exact location of the HSC niche is yet to be clearly identified. Understanding all of the interactions between the stem cells and their microenvironment may yield practical methods for manipulating stem cells to achieve therapeutic outcomes in various disease settings. 80 pp. Englisch. Codice articolo 9783639700428
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Descrizione libro Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Hematopoiesis is maintained throughout the lifetime of an organism by a specialized group of rare cells known as the hematopoietic stem cells (HSCs). These cells are defined by their ability to self-renew to give rise to similar daughter HSCs, and to differentiate into all the lineages of blood cells. The region where HSCs reside to fulfil these tasks is known as the stem cell niche. In a niche, neighboring subsets of cells and extracellular substrates house stem cells and provide specialized signals to modulate stem cell self renewal and progeny production. Many studies have identified key components of the niche required to maintain the HSCs in their primitive state. However, the exact location of the HSC niche is yet to be clearly identified. Understanding all of the interactions between the stem cells and their microenvironment may yield practical methods for manipulating stem cells to achieve therapeutic outcomes in various disease settings. Codice articolo 9783639700428
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Descrizione libro Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Rashidi NargesNarges Rashidi, Ph.D., is currently a post-doctoral researcher at Imperial College London. Her research involves studying the hematopoietic stem cell niche as a potential therapeutic target for leukemia and infection. . Codice articolo 4998586
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