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Formulation Of Phenytoin Complexes For Dissolution Enhancement: Inclusion Complexation Using Β-cyclodextrin And Hp Β-cyclodextrin: Inclusion Complexation Using ¿-cyclodextrin And Hp ¿-cyclodextrin - Brossura
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Phenytoin Inclusion complex prepared by microwave method was used for preparation of FDT by different superdisintegrants by direct compression method. From that the cross-povidone (5%) containing inclusion complex was maximum DT, Wetting time and In-vitro drug release. The FDT containing 1:2 ratio complexes and 5% crospovidone give minimum DT and Wetting time. Then 32 full factorial designs were applied and the tablets were synthesized using different proportions of inclusion complex and crospovidone (%) by direct compression technique. The optimum ratio was 1:2 and 5% which produced highest DT (10.01 sec), Wetting time (9.45 sec.) and cumulative percent drug release (99.51% at 40 min). The solubility and dissolution pattern of Phenytoin were found to be carrier ratio dependent. From evaluation parameters and formulation characterization, it can be concluded that solubility of drug was improved by MW method compared to SE method and pure drug. The tablet contain optimum ratio of inclusion complex and optimum concentration of superdisintegrants give maximum drug release in minimum time period.
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Maulika S Patel, M. Pharmacy in Pharmaceutical Technology in Shree Krishna Institute of Pharmacy, Shankhalpur, becharaji at Gujarat Technological University, Ahmedabad, Gujarat, India.
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Formulation Of Phenytoin Complexes For Dissolution Enhancement
Editore:
LAP LAMBERT Academic Publishing, 2014
ISBN 10: 3659537055
ISBN 13: 9783659537059
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Da: moluna, Greven, Germania
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Maulika PatelMaulika S Patel, M. Pharmacy in Pharmaceutical Technology in Shree Krishna Institute of Pharmacy, Shankhalpur, becharaji at Gujarat Technological University, Ahmedabad, Gujarat, India.Phenytoin Inclusion complex prep. Codice articolo 5163202
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Formulation Of Phenytoin Complexes For Dissolution Enhancement
Editore:
LAP LAMBERT Academic Publishing Mai 2014, 2014
ISBN 10: 3659537055
ISBN 13: 9783659537059
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Phenytoin Inclusion complex prepared by microwave method was used for preparation of FDT by different superdisintegrants by direct compression method. From that the cross-povidone (5%) containing inclusion complex was maximum DT, Wetting time and In-vitro drug release. The FDT containing 1:2 ratio complexes and 5% crospovidone give minimum DT and Wetting time. Then 32 full factorial designs were applied and the tablets were synthesized using different proportions of inclusion complex and crospovidone (%) by direct compression technique. The optimum ratio was 1:2 and 5% which produced highest DT (10.01 sec), Wetting time (9.45 sec.) and cumulative percent drug release (99.51% at 40 min). The solubility and dissolution pattern of Phenytoin were found to be carrier ratio dependent. From evaluation parameters and formulation characterization, it can be concluded that solubility of drug was improved by MW method compared to SE method and pure drug. The tablet contain optimum ratio of inclusion complex and optimum concentration of superdisintegrants give maximum drug release in minimum time period. 152 pp. Englisch. Codice articolo 9783659537059
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Formulation Of Phenytoin Complexes For Dissolution Enhancement : Inclusion Complexation Using ¿-cyclodextrin And Hp ¿-cyclodextrin
Editore:
LAP LAMBERT Academic Publishing, 2014
ISBN 10: 3659537055
ISBN 13: 9783659537059
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Da: AHA-BUCH GmbH, Einbeck, Germania
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Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Phenytoin Inclusion complex prepared by microwave method was used for preparation of FDT by different superdisintegrants by direct compression method. From that the cross-povidone (5%) containing inclusion complex was maximum DT, Wetting time and In-vitro drug release. The FDT containing 1:2 ratio complexes and 5% crospovidone give minimum DT and Wetting time. Then 32 full factorial designs were applied and the tablets were synthesized using different proportions of inclusion complex and crospovidone (%) by direct compression technique. The optimum ratio was 1:2 and 5% which produced highest DT (10.01 sec), Wetting time (9.45 sec.) and cumulative percent drug release (99.51% at 40 min). The solubility and dissolution pattern of Phenytoin were found to be carrier ratio dependent. From evaluation parameters and formulation characterization, it can be concluded that solubility of drug was improved by MW method compared to SE method and pure drug. The tablet contain optimum ratio of inclusion complex and optimum concentration of superdisintegrants give maximum drug release in minimum time period. Codice articolo 9783659537059
Quantità: 1 disponibili
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Formulation Of Phenytoin Complexes For Dissolution Enhancement
Editore:
LAP LAMBERT Academic Publishing Mai 2014, 2014
ISBN 10: 3659537055
ISBN 13: 9783659537059
Nuovo
Taschenbuch
Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Phenytoin Inclusion complex prepared by microwave method was used for preparation of FDT by different superdisintegrants by direct compression method. From that the cross-povidone (5%) containing inclusion complex was maximum DT, Wetting time and In-vitro drug release. The FDT containing 1:2 ratio complexes and 5% crospovidone give minimum DT and Wetting time. Then 32 full factorial designs were applied and the tablets were synthesized using different proportions of inclusion complex and crospovidone (%) by direct compression technique. The optimum ratio was 1:2 and 5% which produced highest DT (10.01 sec), Wetting time (9.45 sec.) and cumulative percent drug release (99.51% at 40 min). The solubility and dissolution pattern of Phenytoin were found to be carrier ratio dependent. From evaluation parameters and formulation characterization, it can be concluded that solubility of drug was improved by MW method compared to SE method and pure drug. The tablet contain optimum ratio of inclusion complex and optimum concentration of superdisintegrants give maximum drug release in minimum time period.Books on Demand GmbH, Überseering 33, 22297 Hamburg 152 pp. Englisch. Codice articolo 9783659537059
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