Metalloproteinases As Targets for Anti-Inflammatory Drugs - Rilegato

Rilegato

ISBN 10: 3764358564 ISBN 13: 9783764358563

Casa editrice: Birkhauser, 1999

Riassunto

This volume describes recent research in the field of metalloproteinases (a family of enzymes that can catalyze tissue degradation), in particular their participation in autoimmune diseases such as rheumatoid arthritis, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates. This volume is intended not only for those active in research into metalloproteinases but also for those with an interest in inflammatory diseases. Thus it addresses both academic and industrial researchers.

Su questo libro

Contenuti:

Structural characteristics of the matrix metalloproteinases.- Matrix metalloproteinase inhibitors.- Role of stromelysin-1 in cartilage metabolism.- Matrix metalloproteinases in neuro-inflammatory disease.- Membrane type matrix metalloproteinases: Regulators of focal proteolysis.- Aggrecanase and cartilage proteoglycan degradation.- Overview of the biological roles of metalloproteinases in health and disease.- Adhesion molecule sheddases.- TNF? converting enzyme.

Su questa edizione

• Editore: Birkhauser
• Data di pubblicazione: 1999
• ISBN 10: 3764358564
• ISBN 13: 9783764358563
• Rilegatura: Copertina rigida
• Numero di pagine: 224
• Redattore: Bottomley Kevin M. K., Bradshaw David, Nixon John S.